中晚期原发性肝癌患者介入治疗预后的影响因素  

Prognostic factors of interventional therapy in patients with advanced primary liver cancer

作　　者：戴璐 刘栋利 李爽爽 曹阳博 DAI Lu;LIU Dong-li;LI Shuang-shuang;CAO Yang-bo(Interventional Operation Room,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区：[1]郑州大学第一附属医院介入手术室,郑州450052

出　　处：《医药论坛杂志》2023年第6期32-35,共4页Journal of Medical Forum

基　　金：河南省中青年医学健康创新项目(YXKC2020037)。

摘　　要：目的 了解中晚期原发性肝癌患者介入治疗后患者的生命质量及心理状况,分析介入治疗中晚期原发性肝癌患者预后的影响因素。方法 采用便利抽样法选择于2019年1月至2022年6月份在郑州大学第一附属医院区介入科住院的原发性肝癌患者作为研究对象。采取问卷调查的方式收集病人基本信息,采用肝胆肿瘤患者生命质量测定量表和医院焦虑抑郁自评量表采集患者的生命质量和焦虑抑郁水平。结果 98例中晚期原发性肝癌患者介入治疗后FACT-HEP量表总评分为(151.06±15.62),其中身体状况、社会状况、情感状况、功能状况、肝胆特异性评分分别为(22.87±3.04)、(22.82±2.93)、(18.42±2.70)、(22.73±2.97)、(64.22±6.88);98例患者中焦虑的可疑存在和肯定存在分别为22例(22.45%)、15例(15.31%);抑郁的可疑存在和肯定存在分别为27例(27.55%)、16例(16.33%)。影响中晚期原发性肝癌患者介入治疗后FACT-HEP评分的因素包括:年龄(β=-8.542)、家庭月收入(β=3.423)、患病时间(β=-4.693)、焦虑(β=-3.443)、抑郁(β=-3.212)。结论 临床工作中应根据患者的年龄、家庭月收入、患病时间、心理状况实施针对性康复评估与干预措施,提高患者的生命质量。Objective To investigate the quality of life and psychological status of patients with advanced primary liver cancer after interventional therapy,and to analyze the prognostic factors of patients with advanced primary liver cancer after interventional therapy.Methods Inpatients with primary liver cancer in the oncology interventional ward of the First Affiliated Hospital of Zhengzhou University from January 2019 to June 2022 were selected as subjects by convenience sampling method.The basic information of patients was collected by questionnaire.The quality of life scale for patients with hepatobiliary tumor and the hospital anxiety and depression self-rating scale were used to collect the quality of life and anxiety and depression level of patients.Results The total score of FACT-HEP scale in 98 patients with advanced primary liver cancer after interventional therapy was(151.06±15.62).The scores of physical status,social status,emotional status,functional status and hepatobiliary specificity were(22.87±3.04),(22.82±2.93),(18.42±2.70),(22.73±2.97) and(64.22±6.88),respectively.Among the 98 patients,22(22.45%) and 15(15.31%) were suspected and certain of anxiety,respectively.There were 27 cases(27.55%) of suspicious depression and 16 cases(16.33%) of certain depression.Factors influencing FACT-HEP score of patients with advanced primary liver cancer after interventional therapy included age(β=-8.542),monthly family income(β=3.423),duration of disease(β=-4.693),anxiety(β=-3.443),depression(β=-3.212).Conclusion In clinical work,targeted rehabilitation assesment and intervention measures should be implemented according to patients' age,family monthly income,duration of illness and psychological status to improve the quality of life of patients.

关 键 词：原发性肝癌 介入治疗 预后 焦虑 抑郁 生命质量 

分 类 号：R735.7[医药卫生—肿瘤]