Diabetes more than retinopathy,it’s effect on the anterior segment of eye  

作　　者：Arvind Kumar Morya Prasanna Venkatesh Ramesh Kirandeep Kaur Bharat Gurnani Aarti Heda Karan Bhatia Aprajita Sinha 

机构地区：[1]Department of Ophthalmology,All India Institute of Medical Sciences,Hyderabad 508126,Telangana,India [2]Glaucoma and Research,Mahathma Eye Hospital Private Limited,Tennur,Trichy 620001,Tamil Nadu,India [3]Pediatric Ophthalmology and Strabismus,Sadguru Netra Chikitsalaya,Sadguru Seva Sangh Trust,Janaki-Kund,Chitrakoot 485334,Madhya Pradesh,India [4]Cornea and Refractive Services,Sadguru Netra Chikitsalaya,Sadguru Seva Sangh Trust,Janaki-Kund,Chitrakoot 485334,Madhya Pradesh,India [5]Department of Ophthalmology,National Institute of Ophthalmology,Pune 411000,Maharashtra,India [6]Department of Ophthalmology,Manaktala Eye and Maternity Home,Meerut 250001,Uttar Pradesh,India [7]Department of Ophthalmology,Worcestershire Acute Hospital,Worcestershire 01601,United Kingdom

出　　处：《World Journal of Clinical Cases》2023年第16期3736-3749,共14页世界临床病例杂志

摘　　要：Diabetes mellitus(DM)is one of the chronic metabolic noncommunicable diseases that has attained worldwide epidemics.It threatens healthy life around the globe,with mild-to-severe secondary complications and leads to significant illness including nephropathy,neuropathy,retinopathy,and macrovascular abnormalities including peripheral vasculopathy,and ischaemic heart disease.Research into diabetic retinopathy(DR),which affects one-third of persons with diabetes,has made considerable strides in recent years.In addition,it can lead to several anterior segment complications such as glaucoma,cataract,cornea,conjunctiva,lacrimal glands and other ocular surface diseases.Uncontrolled DM also caused gradual damage to corneal nerves and epithelial cells,which raises the likelihood of anterior segment diseases including corneal ulcers,dry eye disease,and chronic epithelial abnormalities.Although DR and other associated ocular complications are well-known,the complexity of its aetiology and diagnosis makes therapeutic intervention challenging.Strict glycaemic control,early detection and regular screening,and meticulous management is the key to halting the progression of the disease.In this review manuscript,we aim to provide an in-depth understanding of the broad spectrum of diabetic complications in the anterior segment of the ocular tissues and illustrate the progression of diabetes and its pathophysiology,epidemiology,and prospective therapeutic targets.This first such review article will highlight the role of diagnosing and treating patients with a plethora of anterior segment diseases associated with diabetes,which are often neglected.

关 键 词：DIABETES Ocular surface CATARACT GLAUCOMA Lens UVEA 

分 类 号：R587.2[医药卫生—内分泌] R774.1[医药卫生—内科学]