卵巢交界性上皮性肿瘤的临床病理特征分析  

Clinicopathological Features Analysis of Ovarian Junctional Epithelial Tumor

作　　者：徐汉武 Xu Han-wu(Chaoyang District Maternal and Child Health Hospital,Beijing 100021,China)

机构地区：[1]北京市朝阳区妇幼保健院,北京100021

出　　处：《中外医药研究》2023年第1期138-140,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:分析卵巢交界性上皮性肿瘤(BOT)的临床病理特征。方法:回顾性分析2014年1月—2022年1月北京市朝阳区妇幼保健院收治的120例BOT患者的临床资料。分析BOT患者的临床病理特征与复发影响因素。结果:120例BOT患者的临床症状主要为盆腔有包块、下腹疼痛、腹胀。病理检查显示,黏液性BOT 62例(51.67%)、浆液性BOT 33例(27.50%)、其他BOT 25例(20.83%)。随访8~104个月,共8例患者复发,复发率6.67%。logistic回归分析显示,临床分期非Ⅰa期、存在肿瘤包膜破裂、存在微浸润、糖类抗原125(CA125)异常、糖类抗原-199(CA199)异常是复发危险因素(P<0.05)。结论:BOT临床多无明显症状,主要通过超声与标志物辅助诊断,手术治疗是临床治疗BOT主要方式,临床分期非Ⅰa期、存在肿瘤包膜破裂、存在微浸润、CA125异常、CA199异常是复发的危险因素。Objective:To analyze the clinicopathological characteristics of ovarian junctional epithelial tumors(BOT).Methods:The clinical data of one hundred and twenty patients with BOT admitted to Chaoyang District Maternal and Child Health Hospital from January 2014 to January 2022 were retrospectively analyzed.The clinicopathological characteristics and recurrence influencing factors of BOT patients were analyzed.Results:The clinical symptoms of one hundred and twenty BOT patients were mainly masses in the pelvis,lower abdominal pain and abdominal distension.Pathological examination showed sixty-two cases(51.67%)of mucinous BOT,thirty-three cases(27.50%)of plasmacytic BOT,and twenty-five cases(20.83%)of other BOT.The follow-up ranged from 8 to 104 months,and a total of eight patients recurred,with a recurrence rate of 6.67%.logistic regression analysis showed that clinical stage non-stage Ia,the presence of tumor envelope rupture,the presence of microinfiltration,abnormal glycoantigen 125(CA125),and abnormal glycoantigen-199(CA199)were risk factors for recurrence(P<0.05).Conclusion:BOT is mostly clinically asymptomatic,mainly diagnosed by ultrasound with marker-assisted diagnosis,surgery is the main clinical treatment for BOT,and clinical stage non-stage Ia,presence of tumor envelope rupture,presence of microinfiltration,abnormal CA125,and abnormal CA199 are risk factors for recurrence.

关 键 词：卵巢交界性上皮性肿瘤 病理特征 危险因素 

分 类 号：R73[医药卫生—肿瘤]