稀有人参皂苷生物转化的研究进展  

Research Progress on the Biotransformation of Rare Ginsenosides

作　　者：袁松竹 王斌 周旋 赵升铭 王义[1,2] 雷军 陈屏[1,2] YUAN Songzhu;WANG Bin;ZHOU Xuan;ZHAO Shengming;WANG Yi;LEI Jun;CHEN Ping(College of Life Science,Jilin Agricultural University,Changchun 1301182,China;Jilin Engineering Research Center for Ginseng Genetic Resources Development and Utilization,Changchun 130118,China)

机构地区：[1]吉林农业大学生命科学学院,吉林长春130118 [2]吉林省人参基因资源开发与利用工程研究中心,吉林长春130118

出　　处：《食品工业科技》2023年第12期480-489,共10页Science and Technology of Food Industry

基　　金：吉林省教育厅“十三五”科学技术项目(JJKH20200362KJ);吉林省科技发展计划(20190201171JC)。

摘　　要：人参皂苷作为人参中的主要活性成分,被广泛应用于食品和药品中。人参皂苷因化学结构差异导致其具有不同的性质和功能。具有高活性的稀有人参皂苷在自然界中含量很低,限制了人参皂苷资源的利用。通过不同方法将高含量人参皂苷转化为稀有人参皂苷是获得稀有人参皂苷的重要途径。本文以人参皂苷的结构、药理作用为基础,综述生物修饰法对人参皂苷的糖基水解和母核结构的影响,并对稀有人参皂苷在食品、药品中应用的研究现状、未来发展趋势进行了分析,为改善人参皂苷资源应用提供理论依据。As the main active component in ginseng,ginsenoside is widely used in food and medicine.Ginsenosides have different properties and functions due to their different chemical structures.The content of rare ginsenosides with high activity is very low in nature,which limits the utilization.It is an important way to obtain rare ginsenosides by transforming high content ginsenosides into rare ginsenosides through different methods.Based on the structure and pharmacology of ginsenosides,this paper reviews the effects of biotransformation on the glycosyl hydrolysis and parent nucleus structure of ginsenosides,and it analyzes the application status and future development trend of rare ginsenosides in food and medicine,providing a theoretical basis for improving the application of ginsenosides resources.

关 键 词：稀有人参皂苷 人参皂苷衍生物 生物转化 糖基水解 糖基化 

分 类 号：R284[医药卫生—中药学]