不同人工晶状体屈光度计算公式在浅前房白内障患者中的准确性meta分析  

Accuracy of different intraocular lens power calculation formulas in cataract patients with shallow anterior chamber:a meta-analysis

作　　者：李小禹 杨丽 海玥 谭青青[1] 兰长骏[1] 廖萱[1] Li Xiaoyu;Yang Li;Hai Yue;Tan Qingqing;Lan Changjun;Liao Xuan(Department of Ophthalmology,Affiliated Hospital of North Sichuan Medical College,Medical School of Ophthalmology&Optometry,North Sichuan Medical College,Nanchong 637000,China)

机构地区：[1]川北医学院附属医院眼科、川北医学院眼视光医学院,南充637000

出　　处：《中华实验眼科杂志》2023年第6期576-581,共6页Chinese Journal Of Experimental Ophthalmology

基　　金：四川省科技厅自然科学基金项目(23NSFSC1940);南充市市校科技战略合作项目(22SXFWDF0003)。

摘　　要：目的系统比较不同人工晶状体(IOL)屈光度计算公式在浅前房白内障患者中的准确性。方法计算机检索外文数据库MEDLINE、EMBASE、Cochrane Library以及中文数据库中国知网、万方数据、维普数据库自建库起至2020年8月发表的关于IOL屈光度计算公式在浅前房白内障患者中的准确性同行评议文献,根据纳入标准和排除标准进行文献筛选、资料提取和质量评价,选择不同公式间平均绝对误差(MAE)的平均差(MD)作为观察指标,采用RevMan 5.3软件进行meta分析。结果本研究共纳入7篇文献,总计499眼。对6种IOL屈光度计算公式(Barrett UniversalⅡ、Haigis、SRK/T、Hoffer Q、Holladay 1和Holladay 2)进行比较结果显示,Barrett UniversalⅡ公式的MAE低于Hoffer Q公式(MD:0.11 D;95%CI:0.05~0.17 D;P<0.001)、Haigis公式(MD:0.08 D;95%CI:0.03~0.13 D;P=0.002)和Holladay 2公式(MD:-0.06 D;95%CI:-0.11~-0.01 D;P=0.020),差异均有统计学意义。其余公式之间的配对比较,差异均无统计学意义(均P>0.05)。结论Barrett UniversalⅡ公式在预测浅前房白内障患者IOL屈光度方面优于Hoffer Q公式、Haigis公式和Holladay 2公式。Objective To systematically compare the accuracy of intraocular lens(IOL)power calculation formulas in cataract patients with shallow anterior chamber.Methods A comprehensive literature search was conducted in MEDLINE,EMBASE,Cochrane Library,and the Chinese databases including CNKI,Wanfang,and VIP databases.The peer-reviewed literature on the accuracy of IOL power calculation formulas in cataract patients with shallow anterior chamber was searched from the establishment of the database until August 2020.Literature screening,data extraction and quality assessment were performed according to inclusion and exclusion criteria.The mean difference(MD)of mean absolute error(MAE)among different formulas was analyzed.Meta-analysis was performed using Revman 5.3 software.Results Seven studies involving 499 eyes were included.The accuracy of six formulas,Barrett UniversalⅡ,Haigis,SRK/T,Hoffer Q,Holladay 1 and Holladay 2,was evaluated.The MAE of Barrett UniversalⅡwas significantly lower than that of Hoffer Q(MD=0.11 D;95%CI:0.05-0.17 D;P<0.001),Haigis(MD=0.08 D;95%CI:0.03-0.13 D;P=0.002),and Holladay 2(MD=-0.06 D;95%CI:-0.11--0.01 D;P=0.020).No significant difference was found in the remaining pairwise comparisons(all at P>0.05).Conclusions The Barrett UniversalⅡformula is more accurate than Hoffer Q,Haigis,and Holladay 2 formulas in predicting IOL power in cataract patients with shallow anterior chamber.

关 键 词：白内障 人工晶状体 屈光误差 前房 META分析 

分 类 号：R776.1[医药卫生—眼科]