Qualifying the suitability of living donor livers for pediatric liver transplantation:are we doing the right thing?  

作　　者：Henkjan J.Verkade Frans C.J.Cuperus Aad P.van den Berg 

机构地区：[1]Division of Pediatric Gastroenterology and Hepatology,Department of Pediatrics,University of Groningen,Beatrix Children’s Hospital,University Medical Center Groningen,Groningen,The Netherlands [2]Department of Gastroenterology and Hepatology,University of Groningen,University Medical Center Groningen,Groningen,The Netherlands

出　　处：《Hepatobiliary Surgery and Nutrition》2023年第3期462-464,共3页肝胆外科与营养（英文）

摘　　要：Over the last decades,liver transplantation has become the standard care for many forms of end-stage liver disease,both in adults and in children.The prognosis after pediatric liver transplantation(pLT)has steadily increased up to a patient survival at 5 years of 85%and an estimated graft half life of 31 years(1,2).In the early days of pLT,the transplanted organ originated from deceased donors.Since 1990,adult-to-child living donor liver transplantation(LDLT)programs have developed,which rapidly gained popularity,particularly in Europe and Asia(2,3).A major stimulus for LDLT has been the limited availability of deceased donors.The indications for liver transplantation have expanded,particularly for adult patients,at a higher rate than the availability of donor organs.Moreover,the quality of donor organs has steadily declined,resulting in a decreased utilization of livers from deceased donors for transplantation(4).The limited availability of qualified deceased donor livers has further stimulated LDLT:in Europe,for example,the percentage of living donor organs used for pLT increased from 7%before 2000 to 40%since 2010(1).

关 键 词：STEATOSIS graft survival pediatric liver transplantation(pLT) patient survival 

分 类 号：R657.3[医药卫生—外科学]