子宫肌瘤患者子宫腺肌病发病情况及相关影响因素调查  

Investigate the Incidence and Influencing Factors of Adenomyosis in Patients with Uterine Fibroids

作　　者：倪爱华 NI Aihua(Leping Maternal and Child Health Hospital,Leping 333300,China)

机构地区：[1]乐平市妇幼保健院,江西乐平333300

出　　处：《中国医药指南》2023年第17期120-122,共3页Guide of China Medicine

摘　　要：目的调查分析子宫肌瘤患者子宫腺肌病发病情况及相关影响因素。方法本研究以2020年1月至2022年1月医院收治的82例子宫肌瘤患者为对照组,同期选取53例子宫肌瘤合并子宫腺肌病患者为研究组。采取回顾性分析的方式,对两组患者有关临床资料予以对比分析,统计其影响因素。结果两组流产次数、哺乳时间、HOMA-IR、CA125、血中性粒细胞、血红蛋白、血NLR、血PLR以及合并乳腺结节资料比较,差异有统计学意义(P<0.05)。以单因素分析中差异有统计学意义的因素作为自变量进行多因素回归分析发现,流产次数≥3次、HOMA-IR≥2.69、CA125≥35 U/mL及血红蛋白<60 g/L是子宫肌瘤患者合并子宫腺肌病的高危影响因素,哺乳时间≥6个月是保护因素(P<0.01)。结论影响子宫肌瘤合并子宫腺肌病的因素有很多,流产次数较多、高水平的CA125和HOMA-IR,可有效的预测子宫肌瘤合并子宫腺肌病的形成,哺乳时间≥6个月是该疾病的保护因子。临床应提倡母乳喂养,并合理延长哺乳期间,以有效避免子宫肌瘤合并子宫腺肌病的发生。Objective To investigate and analyze the incidence and related influencing factors of adenomyosis in patients with uterine fibroids.Methods In this study,82 patients with uterine fibroids admitted to the hospital from January 2020 to January 2022 were selected as the control group,and 53 patients with uterine fibroids combined with adenomyosis were selected as the study group during the same period.By retrospective analysis,the clinical data of the two groups were compared and analyzed,and the influencing factors were counted.Results There were statistically significant differences between the two groups in the number of abortions,lactation time,HOMA-IR,CA125,blood neutrophils,hemoglobin,blood NLR,blood PLR and combined breast nodules(P<0.05).Multivariate regression analysis using statistically significant factors in univariate analysis as independent variables showed that the number of miscarriages≥3,HOMA-IR≥2.69,CA125≥35 U/mL and hemoglobin<60 g/L were the high-risk factors for uterine fibroids complicated with adenomyosis,and lactation time≥6 months were protective factors(P<0.01).Conclusion There are many factors affecting uterine fibroids combined with adenomyosis,and the high number of miscarriages and high levels of CA125 and HOMA-IR can effectively predict the formation of uterine fibroids combined with adenomyosis,and lactation time≥6 months is a protective factor of the disease.Breastfeeding should be advocated clinically and the breastfeeding period should be reasonably extended to effectively avoid the occurrence of uterine fibroids combined with adenomyosis.

关 键 词：子宫肌瘤 子宫腺肌病 发病情况 影响因素 调查研究 

分 类 号：R737.33[医药卫生—肿瘤]