国家自然科学基金视角下我国精神疾病研究现况及展望  

Research on mental disorders in China:a view from the perspective of the National Natural Science Foundation of China

作　　者：孙宁 苏闫兵[3] 荆琳 杨军 姚刚 朱元贵 Sun Ning;Su Yanbing;Jing Lin;Yang Jun;Yao Gang;Zhu Yuangui(Department of Medical Science,National Natural Science Foundation of China,Beijing 100085,China;Department of Mental Health,the First Hospital of Shanxi Medical University,Taiyuan 030001,China;Shanxi Bethune Hospital Scientific Research Department,Taiyuan 030032,China)

机构地区：[1]国家自然科学基金委员会医学科学部,北京100085 [2]山西医科大学第一医院精神卫生科,太原030001 [3]山西白求恩医院科研部,太原030012

出　　处：《中华精神科杂志》2023年第3期184-192,共9页Chinese Journal of Psychiatry

摘　　要：目的分析1987—2022年国家自然科学基金精神疾病研究项目资助情况,为相关研究开展提供参考依据。方法登录国家自然科学基金委网站检索1987—2022年学科代码为H10的获批国家自然科学基金项目,利用Excel、Origin和VOSviewer软件对项目基本情况和关键词进行分析。结果1987—2022年精神疾病研究获批国家自然科学基金项目共1882项,总资助金额为101807.65万元,涉及16个项目类型。共有182个依托单位获得立项,前4名依次为北京大学、中南大学、上海市精神卫生中心和四川大学,北京、上海、湖南、江苏、广东、四川、浙江获批项目数量在100项以上,其他省区项目占比2001年后逐渐增长,2016—2022年度达到36%。研究疾病主要围绕心境障碍、精神分裂症、成瘾障碍、焦虑障碍和儿童青少年精神障碍等。主要研究方向聚焦于遗传、神经生化、免疫、神经环路、影像等,近5年肠道菌群、神经调控、机器学习等方向较为关注。结论我国精神疾病领域立项项目数量及类型正稳步提升,形成了以京、沪、湘、川等优势研究院校为主,全国百花齐放的新态势。疾病种类符合我国精神疾病流行特征,形成了从微观基因分子到宏观神经网络、解剖与功能相结合的系统探索模式。Objective By analyzing the funded projects in the field of mental disorders of the National Natural Science Foundation of China from 1987 to 2022,the study aimed to provide a reference for related research.Methods The study accessed the website of the National Natural Science Foundation of China to search the approved projects by the Foundation with subject code H10 from 1987 to 2022,and analysed the essentia information and keywords of the projects by Excel,Origin and VOSviewer software.Results From 1987 to 2022,1882 National Natural Science Foundation projects were approved for mental disorder research,with a total funding amount of 1.018076500 billion China yuan,involving 16 study categories,and 182 research centers.A total of 182 research centers were guaranteed the projects.Peking University,Central South University,Shanghai Mental Health Center and Sichuan University were the top four research centers.More than 100 projects were approved for study in Beijing,Shanghai,Hunan,Jiangsu,Guangdong,Sichuan and Zhejiang each.The projects approved in other provinces increased gradually after 2001,taking a share of 36%in 2016-2022.The researchers primarily focused on mood disorders,schizophrenia,addiction disorders,anxiety disorders and adolescent psychiatric disorders,mainly targeting genetics,neurobiochemistry,immunity,neural circuits and brain imaging.The gut flora,neuromodulation,and machine learning,have attracted significant attention in the past five years.Conclusion The research on mental disorders in China has substantially increased and diversified.The research centers in Beijing,Shanghai,Hunan,and Sichuan have been the leading centers in China.The interest disorders in their studies reflect the prevalent features of mental conditions in China.A comprehensive research power from genetic molecules to neural networks,engaging anatomic and functioning studies,has been well established.

关 键 词：精神障碍 国家自然科学基金 基础研究 项目资助 

分 类 号：R749[医药卫生—神经病学与精神病学]