经颅磁刺激联合曲克芦丁注射液治疗脑梗死的效果  

The Effect of Transcranial Magnetic Stimulation Combined with Troxerutin Injection in the Treatment of Cerebral Infarction

作　　者：幸日坤 谢锦伟 陈福良 XING Rikun;XIE Jinwei;CHEN Fuliang(Luoding People's Hospital,Guangdong Province,Luoding 527200,China)

机构地区：[1]广东省罗定市人民医院,广东罗定527200

出　　处：《中国医学创新》2023年第15期10-14,共5页Medical Innovation of China

基　　金：云浮市医学科学技术研究立项项目(2020B059)。

摘　　要：目的:研究经颅磁刺激+曲克芦丁注射液运用于脑梗死中的效果。方法:选择2020年10月-2021年12月罗定市人民医院收治的脑梗死患者60例,按随机数字表法划分成试验组、对照组,各30例。试验组采取经颅磁刺激+曲克芦丁注射液,对照组采取曲克芦丁注射液。治疗6个月后评价患者的总有效率,对比治疗前、治疗6个月后的神经功能缺损评分[美国国立卫生研究院卒中量表(NIHSS)]、Fugl-Meyer运动功能(FMA)评分、日常生活活动能力(Barthel指数)评分、症状积分、平均血流速度(Vm)、搏动指数(PI),统计不良反应(皮疹、嗜睡、头晕),比较两组治疗结果。结果:试验组总有效率(90.00%)高于对照组(66.67%)(P<0.05)。试验组不良反应发生率(6.67%)低于对照组(26.67%)(P<0.05)。治疗前,两组NIHSS、FMA、Barthel评分对比,差异均无统计学意义(P>0.05);治疗6个月后,试验组NIHSS评分低于对照组,FMA、Barthel评分均高于对照组(P<0.05)。治疗前,两组症状积分对比,差异均无统计学意义(P>0.05);治疗6个月后,试验组口眼歪斜、头晕目眩、半身不遂积分均低于对照组(P<0.05)。治疗前,两组脑血流动力学指标对比,差异均无统计学意义(P>0.05);治疗6个月后,试验组Vm大于对照组,PI小于对照组(P<0.05)。结论:经颅磁刺激+曲克芦丁注射液的疗效更好,使患者症状明显减轻,并增强运动能力及神经功能,改善脑组织血液灌注,提升日常生活能力,不良反应少,值得推广。Objective:To study the clinical effects of transcranial magnetic stimulation and Troxerutin Injection in treating the cerebral infarction.Method:A total of 60 cerebral infarction patients admitted to Luoding People's Hospital from October 2020 to December 2021 were selected and divided into the trial group and the control group according to random number table method,with 30 cases in each group.The trial group received transcranial magnetic stimulation and Troxerutin Injection,the control group received Troxerutin Injection.The total effective rate of the patients was evaluated 6 months after treatment,the national institute of health stroke scale(NIHSS),Fugl-Meyer assessment(FMA),activities of daily living(Barthel index),clinical symptom scores,mean blood velocity(Vm),pulsatility index(PI)were compared before and 6 months after treatment.Adverse reactions(rash,drowsiness,dizziness)were counted and the treatment results of the two groups were compared.Result:The total effective rate in the trial group(90.00%)was higher than that of the control group(66.67%)(P<0.05);the incidence of adverse reactions in the trial group(6.67%)was lower than that in the control group(26.67%)(P<0.05).Before treatment,there were no significant differences in NIHSS,FMA and Barthel scores between the two groups(P>0.05);6 months after treatment,NIHSS score in the trial group was lower than that in the control group,FMA and Barthel index scores were higher than those in the control group(P<0.05).Before treatment,there were no significant differences in clinical symptom scores between the two groups(P>0.05);6 months after treatment,the facial paralysis,dizziness and hemiplegia symptom scores in the trial group were lower than those in the control group(P<0.05).Before treatment,there were no significant differences in the cerebral hemodynamics indicators between the two groups(P>0.05);6 months after treatment,Vm value in the trial group was higher than that in the control group,PI was lower than that in the control group(P<0.05).Conclusion:

关 键 词：脑梗死 经颅磁刺激 曲克芦丁注射液 神经功能 

分 类 号：R743.33[医药卫生—神经病学与精神病学]