肝癌术后化疗患者肝脏脂肪变性经超声声衰减成像定量评估的鉴别效果  

Analysis of the Differential Effect of Ultrasonic Attenuation Imaging Quantitative Assessment of Hepatic Steatosis in Patients with Hepatocellular Carcinoma undergoing Postoperative Chemotherapy

作　　者：姜阳[1] 杨欣[1] 王鑫[2] 孙洪洋 王婷 王超[1] JIANG Yang;YANG Xin;WANG Xin;SUN Hongyang;WANG Ting;WANG Chao(Jiamusi Central Hospital,Heilongjiang Province,Jiamusi 154002,China;不详)

机构地区：[1]黑龙江省佳木斯市中心医院,黑龙江佳木斯154002 [2]黑龙江省佳木斯市妇幼保健院

出　　处：《中国医学创新》2023年第15期124-127,共4页Medical Innovation of China

摘　　要：目的:研究肝癌术后化疗患者肝脏脂肪变性经超声声衰减成像(ATI)定量评估的鉴别效果。方法:选择2018年2月-2021年8月佳木斯市中心医院收治的160例肝癌术后化疗患者,将所有受试者按照肝脏脂肪变性严重程度分为轻度组44例、中度组62例及重度组54例。比较三组年龄、性别、体重指数(BMI)及血脂指标水平;比较三组声衰减系数(AC)值及声衰减参数(UAP)值;采用Spearman相关性分析明确AC值及UAP值与肝癌术后化疗患者肝脏脂肪变性严重程度的相关性;采用受试者工作特征(ROC)曲线分析AC值及UAP值对肝癌术后化疗患者肝脏脂肪变性严重程度的鉴别效果。结果:重度组BMI高于轻度组的及中度组,且中度组BMI高于轻度组(P<0.05)。重度组AC值及UAP值均高于轻度组、中度组,且中度组AC值及UAP值均高于轻度组(P<0.05)。AC值及UAP值与肝癌术后化疗患者肝脏脂肪变性严重程度均呈正相关(P<0.05)。经ROC曲线分析发现,AC值及UAP值联合评估肝癌术后化疗患者肝脏脂肪变性严重程度的效能优于上述两项指标单独评估。结论:肝癌术后化疗患者肝脏脂肪变性经ATI定量评估的鉴别效果显著。Objective:To study the differential effect of ultrasonic attenuation imaging(ATI)quantitative assessment of hepatic steatosis in patients with hepatocellular carcinoma undergoing postoperative chemotherapy.Method:A total of 160 patients with hepatocellular carcinoma admitted to Jiamusi Central Hospital after postoperative chemotherapy from February 2018 to August 2021 were selected,and they were divided into mild group(44 cases),moderate group(62 cases)and severe group(54 cases)according to the severity of hepatic steatosis.Age,sex,body mass index(BMI)and blood lipid levels of the three groups were compared;the values of attenuation coefficient(AC)and ultrasonic attenuation parameter(UAP)of the three groups were compared;Spearman correlation analysis was used to determine the correlation between AC and UAP values and the severity of hepatic steatosis in patients with postoperative chemotherapy for hepatocellular carcinoma;receiver operating characteristic(ROC)curve was used to analyze the differential effect of AC and UAP values on the severity of hepatic steatosis in patients with postoperative chemotherapy for hepatocellular carcinoma.Result:The BMI of severe group was higher than those of mild group and moderate group,and the BMI of moderate group was higher than that of mild group(P<0.05).The AC and UAP values of the severe group were higher than those of mild group and moderate group,and the AC and UAP values of moderate group were higher than those of mild group(P<0.05).AC value and UAP value were positively correlated with the severity of hepatic steatosis in patients with hepatocellular carcinoma underwent postoperative chemotherapy(P<0.05).ROC curve analysis showed that AC value and UAP value combined to evaluate the severity of hepatic steatosis in patients with hepatocellular carcinoma underwent postoperative chemotherapy was better than the above two indexes alone.Conclusion:ATI quantitative assessment of hepatic steatosis in patients with hepatocellular carcinoma after chemotherapy has a significant

关 键 词：肝癌 肝脏脂肪变性 声衰减成像 

分 类 号：R735.7[医药卫生—肿瘤]