神经内镜辅助显微镜下单鼻孔经鼻蝶垂体瘤切除术的效果探讨  

Discussion of the Effectiveness of Neuroendoscopy-assisted Microscopic Single-nostril Transsphenoidal Pituitary Tumor Resection

作　　者：张宗强[1] 马晓娟[2] 韩小军 刘博[1] ZHANG Zongqiang;MA Xiaojuan;HAN Xiaojun;LIU Bo(Department of Neurosurgery,Xinjiang Production and Construction Corps Fourth Division Hospital,Yining,Xinjiang Uygur Autonomous Region,835000 China;Department of Gastroenterology,Xinjiang Production and Construction Corps Fourth Division Hospital,Yining,Xinjiang Uygur Autonomous Region,835000 China)

机构地区：[1]新疆生产建设兵团第四师医院神经外科,新疆伊宁835000 [2]新疆生产建设兵团第四师医院消化内科,新疆伊宁835000

出　　处：《世界复合医学》2023年第2期67-70,共4页World Journal of Complex Medicine

摘　　要：目的观察神经内镜辅助显微镜下单鼻孔经鼻蝶垂体瘤切除术的效果。方法选择2018年1月—2021年12月新疆生产建设兵团第四师医院接诊的46例垂体瘤患者,随机分为:观察组(23例,行神经内镜辅助显微镜下单鼻孔经鼻蝶垂体瘤切除术)、对照组(23例,行显微镜下单鼻孔经鼻蝶垂体瘤切除术),评价两组视觉及嗅觉功能、激素水平、临床指标、并发症发生率。结果术前,两组视觉及嗅觉功能、激素水平差异无统计学意义(P>0.05);术后1周,观察组视觉及嗅觉功能、激素水平均比对照组更佳,差异有统计学意义(P<0.05);较之对照组,观察组出血量更少、手术时间与住院时间更短,且肿瘤全切率更高,差异有统计学意义(P<0.05);观察组并发症发生率(8.69%)低于对照组(34.78%),差异有统计学意义(χ^(2)=4.600,P<0.05)。结论对垂体瘤患者行神经内镜辅助显微镜下单鼻孔经鼻蝶垂体瘤切除术,能够提高肿瘤全切率,减少出血量及手术时间,改善视觉、嗅觉功能,降低并发症风险,缩短住院时间。Objective To observe the effect of neuroendoscopy-assisted microscopic single-nostril transsphenoidal pituitary tumor resection.Methods Methods:From January 2018 to December 2021,46 patients with pituitary tumors admitted to the Fourth Division Hospital of Xinjiang Production and Construction Corps were randomly divided into observation group(23 cases,single nostril transsphenoidal pituitary tumor resection under neuroendoscope-assisted microscope)and control group(23 cases,single nostril transsphenoidal pituitary tumor resection under microscope).Visual and olfactory functions,hormone levels,clinical indicators,and incidence of complication were evaluated between groups.Results Before operation,there was no statistically significant difference in visual and olfactory function and hormone levels between the two groups(P>0.05).One week after operation,the visual and olfactory function and hormone level of the observation group were better than those of the control group,and the difference was statistically significant(P<0.05).Compared with the control group,the bleeding volume was less,operation time and hospitalization time of the observation group were shotter,and the total tumor resection rate was higher,the difference was statistically significant(P<0.05).The incidence of complications in the observation group(8.69%)was lower than that in the control group(34.78%),and the difference was statistically significant(χ^(2)=4.600,P<0.05).Conclusion Neuroendoscopy-assisted microscopic singlenostril transsphenoidal pituitary tumor resection in patients with pituitary tumors can improve the rate of complete tumor resection,reduce bleeding and operative time,improve visual and olfactory functions,reduce the risk of complications,and shorten the hospital stay.

关 键 词：神经内镜 垂体瘤 显微镜 单鼻孔经鼻蝶垂体瘤切除术 并发症 

分 类 号：R739[医药卫生—肿瘤]