对比分析改良根治术与保乳手术治疗早期乳腺癌的近远期疗效  

Comparative Analysis of Short-term and Long-term Efficacy of Modified Radical Surgery and Breast-conserving Surgery in the Treatment of Early Breast Cancer

作　　者：戴民[1] 李雷雷 付雪芹 魏娜[1] DAI Min;LI Leilei;FU Xueqin;WEI Na(Department of Breast Surgery,Guizhou Provincial People's Hospital,Guiyang,Guizhou Province,550001 China)

机构地区：[1]贵州省人民医院乳腺外科,贵州贵阳550001

出　　处：《中外医疗》2023年第9期36-40,共5页China & Foreign Medical Treatment

摘　　要：目的对比探究改良根治术与保乳手术治疗早期乳腺癌的近远期疗效。方法方便选取2019年1月—2020年12月期间贵州省人民医院收治的86例早期乳腺癌患者为研究对象,以随机数表法将其分为对照组和观察组,各43例。对照组患者接受改良根治术治疗,观察组接受保乳手术治疗,并随访2年。比较两组围术期指标、创伤后应激障碍筛查量表(PCL-C)评分、心理状态、远期疗效。结果观察组术中出血量、引流量均少于对照组,住院时间、手术时间均短于对照组,差异有统计学意义(P<0.05)。术前,两组PCL-C评分对比,差异无统计学意义(P>0.05);术后,观察组PCL-C中警觉性提高、重新体验、回避麻木3个维度及总分均低于对照组,差异有统计学意义(P<0.05)。术前,两组汉密尔顿焦虑量表(HAMA)评分、汉密尔顿抑郁量表(HAMD)评分对比,差异无统计学意义(P>0.05);术后,观察组HAMA(18.74±3.87)分、HAMD评分(20.22±3.43)分均低于对照组,差异有统计学意义(t=2.549、2.863,P<0.05)。随访2年期间,观察者局部复发率、远处转移率、腋窝淋巴结复发率均低于对照组,差异无统计学意义(P>0.05)。结论与改良根治术治疗相比,应用保乳手术治疗早期乳腺癌所用手术时间更短,术中出血量及引流量更少,应激反应更轻,且可以在保障预后效果的同时,使其维持积极心态,快速出院。Objective To compare the short-term and long-term effects of modified radical surgery and breastconserving surgery in the treatment of early breast cancer.Methods 86 cases of early breast cancer patients admitted to Guizhou Provincial People's Hospital from January 2019 to December 2020 were conveniently selected as the research objects,and they were randomly divided into the control group and the observation group with 43 cases each.The control group received modified radical surgery,while the observation group received breast conserving surgery and was followed up for 2 years.Compare the perioperative indicators,post-traumatic stress disorder screening scale(PCL-C)scores,psychological status,and long-term efficacy between two groups.Results The intraoperative bleeding volume and drainage volume in the observation group were lower than those in the control group,and the hospital stay and surgical time were shorter than those in the control group,the difference was statistically significant(P<0.05).Before surgery,there was no statistically significant difference in PCL-C scores between the two groups(P>0.05).After surgery,the three dimensions of increased alertness,re experience,and avoidance numbness and the total score in the observation group's PCL-C were lower than those in the control group,the difference was statistically significant(P<0.05).Before surgery,there was no statistically significant difference in the Hamilton Anxiety Scale(HAMA)and Hamilton Depression Scale(HAMD)scores between the two groups(P>0.05).After surgery,the HAMA(18.74±3.87)points and HAMD score(20.22±3.43)points of the observation group were lower than those of the control group,the difference was statistically significant(t=2.549,2.863,P<0.05).During the 2-year follow-up period,the local recurrence rate,distant metastasis rate,and axillary lymph node recurrence rate of the observer were lower than those of the control group,the difference was not statistically significant(P>0.05).Conclusion Compared with the modified radical surgery

关 键 词：改良根治术 乳腺癌 早期 保乳手术 局部复发率 远处转移率 

分 类 号：R737.9[医药卫生—肿瘤]