[4+3]Cycloaddition of ketenimines with furocarbenoids:Divergent and efficient synthesis of fused cycloheptatriene and tropone scaffolds  

作　　者：Jin Wang Zhaoyang Li Shengxin Bai Qinghua Zhou Tengteng Wu Zhongyan Hu Xianxiu Xu 

机构地区：[1]Chemical Engineering and Materials Science,Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong,Key Laboratory of Molecular and Nano Probes,College of Chemistry,Ministry of Education,Institute of Molecular and Nano Science,Shandong Normal University,Ji’nan 250014,China

出　　处：《Chinese Chemical Letters》2023年第5期227-231,共5页中国化学快报（英文版）

基　　金：financial support from National Natural Science Foundation of China(Nos.22171168,22001152 and 22101159);Taishan Scholar Program of Shandong Province and the Natural Science Foundation of Shandong Province of China(No.ZR2020QB019)。

摘　　要：An unprecedent[4+3]cycloaddition of furoketenimines with furocarbenoids has been disclosed for the divergent and efficient synthesis of cycloheptafuran and cycloheptapyrrole scaffolds.Zinc chloride acted as promoters for both the formation of these two transient intermediates from isocyanides and ene-yne-ketones,and the subsequent construction of seven-membered ring.Three rings and five bonds were constructed successively in this three-component one-pot domino reaction.

关 键 词：Domino reactions ISOCYANIDES Ene-yne-ketones Cycloheptafuran scaffolds [4+3]cycloaddition 

分 类 号：O626[理学—有机化学]