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作 者:张宏伟 赵光强(综述)[1] 陈小波(审校)[1] Hongwei Zhang;Guangqiang Zhao;Xiaobo Chen(Department of Thoracic SurgeryⅠ,The Third Affiliated Hospital of Kunming Medical University,Yunnan Cancer Hospital,Kunming 650118,China)
机构地区:[1]昆明医科大学第三附属医院云南省肿瘤医院胸外一科,昆明市650118
出 处:《中国肿瘤临床》2023年第11期581-586,共6页Chinese Journal of Clinical Oncology
基 金:云南省“高层次人才培养支持计划”名医专项项目(编号:YNWR-MY-2020-045);云南省院士专家工作站项目(编号:202005AF150044);云南省卫生健康委员会医学后备人才培养计划项目(编号:H-2018026)资助。
摘 要:目前,早期肺癌的标准术式以各类指南推荐的解剖性肺叶切除联合系统性淋巴结清扫术为主。随着人们健康意识的提高以及低剂量螺旋CT(low-dose computed tomography,LDCT)的普及,越来越多的外周型小结节被发现,这些结节的病理组织学多为肺腺癌。近年来,外科治疗技术不断向精准化、微创化方向发展。针对外周型小结节,外科手术方式也在不断发展,其目的在于保留更多肺组织和肺功能的同时,达到对肿瘤的精准切除。本文针对ⅠA期肺腺癌术前影像学、手术方式、淋巴结清扫方式、术中冰冻、病理亚型及新的病理分级系统对ⅠA期肺腺癌的诊断、治疗及预后影响进行综述。Current guidelines recommend anatomic lobectomy combined with systematic lymph node dissection as the standard procedure for early-stage lung cancer.With increasing health awareness and the popularity of low-dose computed tomography(LDCT),more small peripheral nodules are being detected,many of which have a pathological histology of lung adenocarcinoma.In recent years,surgeons have increasingly adopted precise resection techniques that completely remove tumors while preserving lung tissue and function.This approach has made surgical treatment minimally invasive and precise and also improved patient prognosis.This article reviews the impact of preoperative radiographic findings,surgical approaches,lymph node dissection methods,intraoperative frozen sections,pathological subtypes,and new pathological grading systems on the diagnosis,treatment,and prognosis of stageⅠA lung adenocarcinoma.
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