儿童脑内静脉三维相位对比血管成像序列参数优化研究  

Optimization of 3D Phase Contrast Venography for the Assessment of the Cerebral Veins in Children

作　　者：孟宪磊[1] 方佃刚[1] 李志勇[1] 周洋洋[1] 刘龙平 卢宁 肖鑫 曾洪武[1] MENG Xian-lei;FANG Dian-gang;LI Zhi-yong;ZHOU Yang-yang;LIU Long-ping;Lu ning;Xiao Xin;ZENG Hong-wu(Department of Radiology,Shenzhen Children’s Hospital,Shenzhen 518026,P.R.China)

机构地区：[1]深圳市儿童医院放射科,广东深圳518038

出　　处：《中国CT和MRI杂志》2023年第6期21-23,共3页Chinese Journal of CT and MRI

基　　金：深圳市医疗卫生三名工程项目(SZSM202011005)。

摘　　要：目的优化三维相位对比静脉成像MR(3D phase contrast venography,3D PCV)序列,提高其对脑内静脉血管的可视化效果。方法收集健康儿童28名,采用西门子Skyra(德国)3.0T MR扫描仪行厂家原始和优化的3D PCV序列。原始3D PCV序列(原始组)的流速编码(velocity encoding,VENC)为12cm/s,优化3D PCV序列(优化组)的VENC为20cm/s。采用主观评价法对上矢状窦、下矢状窦、直窦、皮质静脉、右乙状窦、左乙状窦、右横窦、左横窦、窦汇进行评分。采用Wilcoxon符号秩检验比较两组图像的主观评分,P<0.05认为差异有统计学意义。结果优化组的上矢状窦(P=0.004)、右乙状窦(P=0.005)、左乙状窦(P<0.001)、右横窦(P<0.001)、左横窦(P=0.01)、直窦(P<0.001)可视化效果优于原始组;原始组和优化组下矢状窦(P=0.556)、皮质静脉(P=1)、窦汇(P=0.287)的可视化效果无差异。结论优化后的3D PCV序列可明显提高儿童大部分脑内静脉的可视化效果,增强诊断信心。Objective The aim of this work was to optimize 3D Phase contrast venography(3D PCV)sequence to improve the visualization effect of cerebral veins.Methods The original and optimized sequences were used to perform 3D PCV in 28 healthy children using a 3.0T MR system(Siemens Skyra,Germany).The velocity encoding(VENC)of the original 3D PCV sequence(original group)was 12cm/s,while the VENC of optimized 3D PCV sequence(optimized group)was 20cm/s.For evaluation,the cerebral veins was divided into 9 segments.These segments were evaluated by two radiologists with experience in pediatric neuroradiology.A scoring system was used to access the quality of visualization.Wilcoxon sign rank test was used to compare the subjective scores of the two groups,and P<0.05 was considered statistically significant.Results The visualizations of Superior sagittal sinus(P=0.004),right Sigmoid sinus(P=0.005),left Sigmoid sinus(P<0.001),right Transverse sinus(P<0.001),left Transverse sinus(P=0.01)and Straight sinus(P<0.001)in the optimized group were better than those in the original group.The visualizations of Inferior sagittal sinus(P=0.556),cortical vein(P=1)and Torcular Herophili(P=0.287)showed no difference between the original group and the optimized group.Conclusion The optimized 3D PCV pulse sequence showed superior results compared to the original 3D PCV for the visualization and evaluation of the venous system in all healthy children volunteers.

关 键 词：儿童 脑内静脉 相位对比静脉成像 

分 类 号：R748[医药卫生—神经病学与精神病学]