蜜蜂级型分化过程中信号通路调控的研究进展  

Advances in the Regulation of Signaling Pathways in Caste Differentiation in Honeybees

作　　者：王舒悦 胡福良[1] Wang Shuyue;Hu Fuliang(College of Animal Sciences,Zhejiang University,Hangzhou 310029,China)

机构地区：[1]浙江大学动物科学学院,杭州310058

出　　处：《中国蜂业》2023年第5期58-61,共4页Apiculture of China

基　　金：财政部和农业农村部:国家现代农业产业技术体系专项(CARS-44);浙江省“三农九方”科技协作计划项目(2022SNJF056)。

摘　　要：级型分化是一种奇妙的自然现象,拥有完全相同基因组的同性物种却可以发育产生完全不同的生物学特征。在蜜蜂中级型分化表现为二型雌蜂,即蜂王和工蜂,二者在遗传物质上没有区别,而其不同表型的产生是由于幼虫阶段营养摄入差异引起的表观遗传差异化修饰最终导致的不同发育途径。由于其机制的复杂性,至今仍未完全阐明营养差异通过何种途径转化为生理信号,调节蜜蜂级型分化过程。本文从信号通路入手,综述了蜜蜂中受关注度最高的EGFR、IIS/TOR、FOXO等三条信号通路的研究进展,为蜜蜂级型分化研究提供信号通路方面的参考。Caste differentiation is a fascinating natural phenomenon,describing homosexual species with identical genomes but develop completely different biological characteristics.Correspondingly,there are two castes of adult female in honeybees,queens and workers,induced by differential nutrition received at the larval stage and resulting in the epigenetic differential modifi cation,which ultimately leads to different development pathways.Due to the complexity of its mechanism,it is still relatively unclear how the nutrient differences can be converted into physiological signals to regulate the process of caste differentiation.Therefore,this article reviews the advances in three signaling pathways had received the highest attention in honeybees,EGFR,IIS/TOR and FOXO,aiming to provide a reference for the study of signaling pathways in caste differentiation in honeybees.

关 键 词：蜜蜂 级型分化 信号通路 

分 类 号：S891[农业科学—特种经济动物饲养]