FS-LASIK与SMILE治疗屈光不正后患者眼表变化分析  

Analysis of Ocular Surface Changes in Patients with Refractive Error Treated with FS-LASIK and SMILE

作　　者：李红 朱飞 LI Hong;ZHU Fei(Department of Ophthalmology,Yulin Traditional Chinese Medicine Hospital,Yulin Shaanxi 719000)

机构地区：[1]榆林市中医医院眼科,陕西榆林719000

出　　处：《医学临床研究》2023年第5期731-734,共4页Journal of Clinical Research

摘　　要：【目的】探讨飞秒激光制瓣准分子激光原位角膜磨镶术(FS-LASIK)与飞秒激光小切口基质透镜取出术(SMILE)治疗屈光不正后患者眼表变化情况。【方法】选取2021年1月至2022年1月在本院行FS-LASIK矫正的屈光不正患者38例作为FS-LASIK组,另外选取同期来本院行SMILE矫正的屈光不正患者38例作为SMILE组,比较两组术前、术后1周、术后1个月、术后3个月、术后6个月眼表疾病指数(OSDI)问卷评分、角膜荧光染色评分、中央泪河高度(TMH)、睑板腺功能评分(LMS)及脂质层厚度。【结果】术后6个月,FS-LASIK组OSDI评分高于SMILE组(P<0.05),术后1周、1个月、3个月OSDI评分较术前增加(P<0.05);两组术后1周、术后1个月角膜荧光素染色评分较术前均提高(P<0.05);两组术后1周、术后1个月TMH较术前提高(P<0.05);两组术前、术后1周、术后1个月、术后3个月、术后6个月LMS、脂质层厚度比较,差异无统计学意义(P>0.05),两组术后6个月脂质层厚度较术前减少(P<0.05)。【结论】FS-LASIK与SMILE两种手术均会对屈光不正患者眼表产生影响,导致患者出现干眼症状,但FS-LASIK术后出现干眼症状更为严重。【Objective】To investigate the changes of ocular surface in patients with ametropia after femtosecond laser flap excimer laser laser in situ keratomileusis(FS-LASIK)and small incision stroma lens extraction(SMILE).【Methods】A total of 38 patients with refractive errors who underwent FS-LASIK correction in our hospital from January 2021 to January 2022 were selected as the FS-LASIK group.In addition,38 patients with refractive errors who underwent SMILE correction in our hospital during the same period were selected as the SMILE group.The two groups were compared in terms of preoperative,postoperative 1 week,postoperative 1 month,postoperative 3 months,and postoperative 6 months,including the Eye Surface Disease Index(OSDI)questionnaire score,corneal fluorescence staining score,central lacrimal height(TMH),meibomian gland function score(LMS),and lipid layer thickness.【Results】Six months after surgery,the OSDI score of the FS-LASIK group was higher than that of the SMILE group(P<0.05),and the OSDI score increased at 1 week,1 month,and 3 months after surgery compared to those before surgery(P<0.05);The corneal fluorescein staining scores of both groups increased at 1 week and 1 month after surgery compared to before surgery(P<0.05);TMH in both groups increased at 1 week and 1 month after surgery compared to before surgery(P<0.05);There was no statistically significant difference in LMS and lipid layer thickness between the two groups before surgery,1 week after surgery,1 month after surgery,3 months after surgery,and 6 months after surgery(P>0.05).The lipid layer thickness of the two groups at 6 months after surgery decreased compared to that before surgery(P<0.05).【Conclusion】Both FS-LASIK and SMILE surgeries can have an impact on the ocular surface of ametropia patients,leading to dry eye symptoms.However,dry eye symptoms are more severe after FS-LASIK surgery.

关 键 词：屈光不正/外科学 激光 准分子/治疗应用 角膜磨镶术 激光原位 眼表现 

分 类 号：R779.6[医药卫生—眼科]