综合疗法治疗急性虹膜炎的临床应用  

Clinical Application of Integrated Therapy for Acute Iriditis

作　　者：曹冬蕾 吴勤[1] 刘建伟 杨春林[1] CAO Donglei;WU Qin;LIU Jianwei;YANG Chunlin(Ophthalmology Department,Qidong Hospital of Traditional Chinese Medicine,Qidong,Jiangsu Province,226200 China)

机构地区：[1]江苏省启东市中医院眼科,江苏启东226200

出　　处：《中外医疗》2023年第14期139-142,共4页China & Foreign Medical Treatment

摘　　要：目的分析综合疗法对急性虹膜炎的治疗效果。方法随机选取2019年1月—2021年12月江苏省启东市中医院眼科收治的急性虹膜炎患者50例,根据患者入院诊治顺序均分至对照组和研究组,各25例。对照组采用西药治疗,研究组实施综合疗法(在对照组基础上联合应用蒲地蓝口服液中成药雾化机雾化熏蒸方案),对比两组临床疗效、症状持续时间、炎症因子水平和复发率。结果观察组总有效率为96.00%,高于对照组的68.00%,眼红、眼痛、畏光、视力下降持续时间均短于对照组,治疗后1、2、6个月复发率分别为0.00%、4.00%和12.00%,明显低于对照组,差异有统计学意义(P<0.05);两组用药前炎症因子水平比较,差异无统计学意义(P>0.05),观察组用药后C反应蛋白为(7.18±1.12)mg/L,白细胞介素-6为(0.40±0.08)ng/L,白细胞介素-8为(0.32±0.05)ng/mL,与对照组数据比较,差异有统计学意义(t=7.016、4.854、4.650,P<0.05)。结论予以急性虹膜炎患者综合疗法,效果明显,可缩短症状持续时间,也可降低炎症因子水平和复发率,有应用价值。Objective To analyze the therapeutic effect of integrated therapy on acute iritis.Methods Fifty patients with acute iriditis admitted to the ophthalmology department of Qidong Hospital of Traditional Chinese Medicine from January 2019 to December 2021 were randomly selected and divided equally into a control group and a study group according to the order of patients'admission to the hospital,with 25 patients in each group.The control group were treated with Western medicine,and the study group implemented integrated therapy(combined application of Pudilan oral liquid Chinese medicine nebulizer nebulization fumigation program on the basis of the control group).The clinical efficacy,duration of symptoms,level of inflammatory factors and recurrence rate of the two groups were compared.Results The total effective rate of the study group was 96.00%,which was higher than that of the control group(68.00%),the duration of eye redness,eye pain,photophobia and vision loss were shorter than that of the control group,and the recurrence rates were 0.00%,4.00%and 12.00%at 1 month,2 months and 6 months after treatment,respectively,which were significantly lower than those of the control group,and the difference was statistically significant(P<0.05).There was no statistically significant difference in the levels of inflammatory factors between the two groups before medication(P>0.05).C-reactive protein was(7.18±1.12)mg/L,interleukin-6 was(0.40±0.08)ng/L,and interleukin-8 was(0.32±0.05)ng/mL in the study group after medication,compared with the control group,the difference was statistically significant(t=7.016,4.854,4.650,P<0.05).Conclusion The combination therapy given to patients with acute iriditis is effective and can shorten the duration of symptoms and also reduce the level of inflammatory factors,and recurrence rate,and has application value.

关 键 词：综合疗法 急性虹膜炎 临床疗效 炎症因子 复发率 

分 类 号：R773[医药卫生—眼科]