乳癌术后方联合西医常规治疗对乳腺癌术后患者中医证候积分及生活质量的影响  

Influence of postoperative prescription of traditional Chinese medicine for breast cancer combined with conventional western medicine treatment on traditional Chinese medicine syndrome score and quality of life of postoperative patients with breast cancer

作　　者：黄双庆 李甜 王晓婷 朱凌翼 张卫红[2] HUANG Shuangqing;LI Tian;WANG Xiaoting;ZHU Lingyi;ZHANG Weihong(General Practice Department of Songnan Community Health Service Center of Baoshan District,Shanghai 200441,China;Breast Surgery Department of Baoshan Branch of Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 201900,China)

机构地区：[1]上海市宝山区淞南镇社区卫生服务中心全科,上海200441 [2]上海中医药大学附属曙光医院宝山分院乳腺外科,上海201900

出　　处：《上海医药》2023年第12期31-33,50,共4页Shanghai Medical & Pharmaceutical Journal

基　　金：上海市卫生健康委员会卫生行业临床研究专项(202140239);上海市科技计划项目(21ZR1447800);上海市科技计划项目(22ZR1446900);宝山区名中医传承工作室项目(BSMZYGZS-201909);2018年上海市“医苑新星”青年医学人才培养资助计划(青年医学人才类-专科与全科项目)。

摘　　要：目的:观察在西药常规治疗基础上加用乳癌术后方对乳腺癌术后患者中医症状、生活质量等的影响。方法:回顾性分析2020年7月至2021年7月上海中医药大学附属曙光医院宝山分院乳腺外科诊治的197例乳腺癌术后患者,按治疗方案分为治疗组(99例)和对照组(98例)。对照组采用西医常规治疗;治疗组在西医常规治疗基础上,于术后1个月开始服用中药乳癌术后方,6个月为1个疗程,治疗2个疗程。比较2个疗程后两组中医证候积分、中医症状疗效评定以及生活质量情况。结果:治疗后,治疗组中医证候积分明显低于对照组(P<0.05);中医症状疗效总有效率为90.91%(90/99),高于对照组的69.39%(68/98,P<0.05)。治疗组治疗后WHOQOL-BREF量表的生理领域、心理领域、社会关系及环境领域评分均较治疗前有所上升(P<0.05),且上升幅度高于对照组(P<0.001)。结论:乳癌术后方联合西医常规治疗可以明显改善乳腺癌术后患者的临床症状,提高生活质量,中医证候疗效确切。Objective:To observe the effect of postoperative prescription of traditional Chinese medicine(TCM)for breast cancer on the basis of conventional western medicine treatment on TCM symptoms and quality of life in patients with breast cancer.Methods:One hundred and ninety-seven cases of postoperative patients with breast cancer diagnosed and treated in Breast Surgery Department of Baoshan Branch of Shuguang Hospital Affiliated to Shanghai University of TCM,Shanghai from July 2020 to July 2021 were retrospectively analyzed,and according to the treatment scheme,and were divided into a treatment group with 99 cases and a control group with 98 cases.The control group was treated with conventional western medicine;on the basis of conventional western medicine treatment,the treatment group began to take Chinese medicine after breast cancer surgery one month after surgery,and six months was one course of treatment,and the treatment had two courses.The TCM syndrome score,TCM symptom efficacy evaluation,and life quality of the two groups after two courses of treatment were compared.Results:After treatment,the score of TCM syndrome in the treatment group was significantly lower than that in the control group(P<0.05);the total effective rate of symptomatic efficacy of TCM was 90.91%(90/99),which was higher than that 69.39%in the control group(68/98,P<0.05).The scores of WHOQOL-BREF scale in the fields of physiology,psychology,social relations,and environment in the treatment group increased(P<0.05),and the treatment group was significantly higher than the control group(P<0.05).Conclusion:Postoperative prescription of TCM for breast cancer combined with conventional western medicine treatment can significantly improve the clinical symptoms of postoperative patients with breast cancer,improve the quality of life,and the TCM syndrome is effective.

关 键 词：乳腺癌 乳癌术后方 生活质量 中医证候积分 

分 类 号：R730.6[医药卫生—肿瘤]