肝细胞癌早期筛查和诊断的研究进展  

Research advances in early screening and diagnosis of hepatocellular carcinoma

作　　者：韩家鑫 宓余强[2] 徐亮[2] HAN Jiaxin;MI Yuqiang;XU Liang(Clinical School of The Second People’s Hospital of Tianjin Medical University,Tianjin 300192,China;Tianjin Hepatopathy Research Institute,Tianjin Second People’s Hospital,Tianjin 300192,China)

机构地区：[1]天津医科大学第二人民医院临床学院,天津300192 [2]天津市第二人民医院天津市肝病医学研究所,天津300192

出　　处：《临床肝胆病杂志》2023年第6期1468-1475,共8页Journal of Clinical Hepatology

基　　金：天津市卫生健康科技项目重点学科专项(TJWJ2022XK034);天津市医学重点学科(专科)建设项目资助(TJYXZDXK-059B);天津市卫生健康委员会中西医结合科研课题重点项目(2021022)。

摘　　要：针对高危人群,早期筛查、早期诊断是实现肝癌很好控制、减轻肝癌负担的重要措施。其中,确定肝癌的高危人群和制定适合的肝癌筛查策略是实现肝癌早期筛查和诊断的关键。肝癌风险评估模型是对肝癌的高危人群便捷和快速识别的重要手段。在肝癌风险分层评估的基础上,应用影像学技术、血清学标志物、液体活组织检查、代谢组学及糖组学等方法,实现肝癌精准早筛、早诊,从而达到早治目的。For the high-risk population,early screening and diagnosis are important measures to achieve good control of liver cancer and reduce the burden of liver cancer,and determining the high-risk population of liver cancer and formulating appropriate liver cancer screening strategies are the key to realizing the early screening and diagnosis of liver cancer.The risk assessment model for liver cancer is an important method for rapid and convenient identification of the high-risk population of liver cancer.Based on the risk stratification of liver cancer,the methods such as imaging technology,serological markers,liquid biopsy,metabolomics,and glycomics can be used for accurate early screening and diagnosis of liver cancer,so as to achieve the goal of early treatment.

关 键 词：癌 肝细胞 癌症早期检测 早期诊断 

分 类 号：R735.7[医药卫生—肿瘤]