Noninvasive identificational diagnosis of diabetic nephropathy and non-diabetic renal disease based on clinical characteristics of Traditional Chinese Medicine symptom pattern and conventional medicine  

作　　者：QU Yilun CHENG Haimei WANG Qian LI Shuang DUAN Shuwei FENG Zhe LI Weizhen JIANG Shuangshuang YANG Hongtao MAO Yonghui GENG Yanqiu LI Jijun LIU Yuning TIAN Jinzhou LIU Hongfang DONG Zheyi CHEN Xiangmei 

机构地区：[1]Department of Nephrology,First Medical Center of Chinese PLA General Hospital,Nephrology Institute of the Chinese People's Liberation Army,State Key Laboratory of Kidney Diseases,National Clinical Research Center for Kidney Diseases,Beijing Key Laboratory of Kidney Disease Research,Beijing 100853,China [2]Department of Nephrology,The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300381,China [3]Department of Nephrology,Beijing Hospital,Beijing 100730,China [4]Department of Nephrology,the Third Medical Center of PLA General Hospital,Beijing 100039,China [5]Department of Nephrology,the Forth Medical Center of PLA General Hospital,Beijing 100048,China [6]Department of Nephrology,Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine,Beijing 100700,China [7]Three Departments of Encephalopathy,Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine,Beijing 100700,China [8]Department of Endocrinology,Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine,Beijing 100700,China

出　　处：《Journal of Traditional Chinese Medicine》2023年第3期588-593,共6页中医杂志（英文版）

基　　金：Supported by the State Key Research and Development Program:Study on the Core Pathogenesis and Clinical Evolution of Damp-heat Symptom in Diabetic Nephropathy(2018YFC1704203);Key Technologies and Varieties Development of New TCM Drugs Based on Big Data(2019Zx09201-005);the Beijing Science and Technology Plan Project:Correlation between Clinical Phenotype and Pathological Diagnosis of Type 2 Diabetic Nephropathy(D171100002817002);the National Natural Science Foundation of China for Youth:Effect of miR-155 on Inhibition of Macrophage Autophagy by m TOR in Diabetic Nephropathy(81700629)。

摘　　要：OBJECTIVE:To study the clinical characteristics relating to differential diagnosis of diabetic nephropathy(DN) and non-diabetic renal disease(NDRD).METHODS:The subjects were patients with type 2 diabetes mellitus(T2DM) complicated with chronic kidney disease(CKD).Western medical history data and Traditional Chinese Medicine(TCM) symptom pattern were collected,and logistic regression was used to analyze.RESULTS:Blood deficiency pattern [odds ratio(OR) = 2.269,P = 0.017] and Qi stagnation pattern(OR = 1.999,P = 0.041) are independently related to DN.CONCLUSIONS:TCM factors blood deficiency pattern and Qi stagnation pattern are relating to differential diagnosis of DN and NDRD.

关 键 词：diabetes mellitus type 2 renal insufficiency CHRONIC diabetic nephropathies non-diabetic renal disease syndrome complex 

分 类 号：R587.2[医药卫生—内分泌] R692.9[医药卫生—内科学]