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Innovative approaches to managing chronic multimorbidity:A multidisciplinary perspective
《World Journal of Clinical Cases》2025年第19期99-106,共8页Haewon Byeon 
Supported by Basic Science Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Education,No.NRF-RS-2023-00237287.
The rising prevalence of chronic multimorbidity poses substantial challenges to healthcare systems,necessitating the development of innovative management strategies to optimize patient care and system efficiency.The s...
关键词：Chronic multimorbidity High complexity unit Multidisciplinary approach Patient-centered care Integrated care model Hospitalization metrics 
Exogenous ketogenic supplements can mitigate the susceptibility to Alzheimer's disease induced by chronic sleep deprivation:emerging role of Sirt1 in ferroptosis
《Food Science and Human Wellness》2025年第3期1034-1044,共11页Yueqi Yang Xueyan Wang Lu Chen Ning Zhang Shilei Ji Zhengping Wang Jun Han Yuming Wang Min Wen 
supported by Natural Science Foundation of Shandong province(ZR2021QH022,ZR2021QB198);National Natural Science Foundation of China(82001286);the Open Project of Liaocheng University Animal Husbandry Discipline(319462207-24)。
Emerging evidence supports that sleep disorders are the main risk factor for sporadic Alzheimer's disease(AD),and iron dysregulation may be the link between them.Our previous studies have confirmed that ketogenic diet...
关键词：Sleep loss Alzheimer’s disease Ferroptosis Mitochondrial dysfunction Silent information regulator 1 
Intelligent hydrogel-based dressings for treatment of chronic diabetic wounds
《World Journal of Diabetes》2025年第5期71-88,共18页Huan Liu Li He 
Diabetic wounds represent a significant challenge in the medical field,significantly impacting patient quality of life and imposing a heavy burden on healthcare systems.Intelligent hydrogel dressings have attracted si...
关键词：Intelligent dressings Diabetic wounds HYDROGEL Stimuli-responsive polymers Drug delivery systems 
Nonlinear association between serum albumin levels and allcause mortality in elderly patients with chronic aortic regurgitation
《Journal of Geriatric Cardiology》2025年第4期423-432,共10页Ming-Hui LI Qing-Rong LIU Zhen-Yan ZHAO Hai-Yan XU Yong-Jian WU the CHINA-VHD Collaborators 
supported by the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(2017-12M-3-002);the Central High Level Hospital Clinical Research Operating Expenses,China(Zero Balance 2022-GSP-GG-15);the Natural Science Foundation Project of the Inner Mongolia Autonomous Region of China(2022LHQN08003).
BACKGROUND Low serum albumin levels are established predictors of adverse outcomes in various cardiovascular conditions.However,the role of serum albumin in mortality among elderly patients with chronic aortic regurgi...
关键词：risk factor chronic aortic regurgitation ar elderly patients low serum albumin chronic aortic regurgitation all cause mortality serum albumin nonlinear association 
Effects of Qingyangshen glycosides on neuroplasticity in a mouse model of social defeat
《Animal Models and Experimental Medicine》2025年第4期581-594,共14页Jingru Wang Weishi Chen Qiang Zhu Yao Liu Zheng Kang Dingding Liu Guirong Zeng 
Guizhou Administration of TCM,Traditional Chinese medicine,Ethnic Medicine Science and Technology Research Special Project,Grant/Award Number:QZYY-2022-008;Subsidy Fund for Scientific Research and Innovation Exploration Project,National Natural Science Foundation of China of Guizhou University of Traditional Chinese Medicine,Grant/Award Number:2018YFC170810502;Science and Technology Fund Project of Guizhou Provincial Health Commission,Grant/Award Number:gzwkj2023-147;Development of animal models for drug discovery-brain diseases.National Research and Development Project of China,MOST,Grant/Award Number:2023YFF0724802.
Background:Qingyangshen(Cynanchum otophyllum C.K.Schneid)is a folk drug for treating depression and other mental disorders induced by social defeat stress.Neuroplasticity in the hippocampus is essential for the modula...
关键词：chronic social defeat DCX NEUROPLASTICITY PSD-95 QYS glycosides SYN 
Impact of depression, anxiety, inflammatory factors, and stress levels on treatment outcomes in patients with chronic trauma
《World Journal of Psychiatry》2025年第3期19-22,共4页Wei Zhao Wei-Guan Chen Long-Yao Zhang Zhi-Ming Cui Xue-Jian Wang 
Supported by Research Project of Nantong Health and Health Commission,No.MS2023041 and No.MA2021017;Science and Technology Program of Nantong City,No.Key03 and No.JCZ2022040;Kangda College of Nanjing Medical University,No.KD2021JYYJYB025,No.KD2022KYJJZD019,and No.KD2022KYJJZD022;Nantong Young Medical Expert,No.46.
This editorial discusses a recent article published by Li et al in 2024,which highlights a critical yet underexplored dimension of chronic wound care:The impact of psychological factors such as depression and anxiety ...
关键词：Chronic trauma DEPRESSION ANXIETY Therapeutic outcomes EDITORIAL 
Optimizing patient outcomes in interstitial lung disease through preand post-transplant management strategies
《World Journal of Transplantation》2025年第3期38-50,共13页Vasiliki E Georgakopoulou 
Interstitial lung diseases(ILD)encompass a diverse group of over 200 chronic pulmonary disorders characterized by varying degrees of inflammation and fibrosis,which can lead to severe respiratory impairment.Lung trans...
关键词：Interstitial lung disease Lung transplantation Chronic lung allograft dysfunction Pre-transplant evaluation IMMUNOSUPPRESSION 
Osteopathic Manual Therapy in Rural Outpatient Rehabilitation Provides Continued Improvement in Functional Status for Patients with Chronic Non-Specific Back Pain: Results of An Eleven-Year Longitudinal Study
《Open Journal of Therapy and Rehabilitation》2025年第1期20-29,共10页Daniel J. Wilson Jennie L. Gorham Shanliang Lui Todd Daniel 
Background: Osteopathic manual treatment (OMT) has been reported to have positive initial results for subjects with chronic non-specific back pain in a rural safety-net hospital. However, the effects of OMT following ...
关键词：Manual Therapy Low Back Pain RURAL 
Repetitive Transcranial Magnetic Stimulation(rTMS)Improves Cognitive Impairment and Intestinal Microecological Dysfunction Induced by High-Fat Diet in Rats
《Research》2025年第1期356-370,共15页Kangyu Jin Bing Chen Shengyi Han Jingyi Dong Shangping Cheng Bin Qin Jing Lu 
support of funds from the National Natural Science Foundation(82271561);the Medical Science and Technology Project of Zhejiang Province(2022RC024).
Consuming a high-fat diet(HFD)is widely recognized to cause obesity and result in chronic brain inflammation that impairs cognitive function.Repetitive transcranial magnetic stimulation(rTMS)has shown effectiveness in...
关键词：behavioral assessments repetitive transcranial magnetic stimulation transcranial magnetic stimulation rtms cognitive decline cognitive impairment chronic brain inflammation 
Short-term Effects of Fine Particulate Matter and its Constituents on Acute Exacerbations of Chronic Bronchitis: A Time-stratified Case-crossover Study
《Biomedical and Environmental Sciences》2025年第3期389-393,共5页Jingwei Zhang Jian Zhang Pengfei Li Yandan Xu Xuesong Zhou Xiuli Tang Jia Qiu Zhongao Ding Mingjia Xu Chongjian Wang 
supported by the Natural Science Foundation of Henan Province(Grant No:23230042151);the Support Plan of the Health Commission in the Jinshan District of Shanghai(Grant No.JSFCZK202103);Foundation of National Key Program of Research and Development of China(Grant NO:2016YFC0900803).
Chronic bronchitis(CB),characterized by persistent coughing with mucus production for at least three consecutive months in two successive years and caused by multiple factors[1],is a progressive condition.Acute exacer...
关键词：ACUTE CHRONIC INFLAMMATION 
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