Acupuncture on intrauterine growth restriction associated brain injury:case study including use of magnetic resonance imaging  

作　　者：XIN Zhixiong LI Jiyuan XU Yanni LING Jing JIANG Min YU Yutian 

机构地区：[1]Department of Pediatrics,People's Hospital of Sanshui District,Foshan 528000,China [2]Department of MRI,Beijing Shijitan Hospital,Capital Medical University,Beijing 100038,China [3]Ninth School of Clinical Medicine,Peking University,Beijing 100038,China [4]Foshan Minfound Medical Imaging Diagnostic Center,Foshan 528000,China [5]Department of Gynecology,Shenzhen Traditional Chinese Medicine Hospital,Shenzhen 518033,China [6]Acupuncture Department,Beijing Shijitan Hospital,Capital Medical University,Beijing 100038,China

出　　处：《Journal of Traditional Chinese Medicine》2023年第3期602-605,共4页中医杂志（英文版）

基　　金：Supported by National Natural Science Foundation of China:Mechanisms Studies of γ-frequency Auricular Electroacupuncture Facilitates APP/PS1 Mice Cognition via P2X7R/NLRP3/Caspase-1 Pathway(No.82104980);Beijing Municipal Administration of Hospitals Incubating Program:Mechanisms Studies of Auricular Electroacupuncture on Hypothalamic P2Y1R in the Regulating Body Weight of ob/ob Mice(No.PZ2022005);Youth Grant of Beijing Shijitan Hospital:Mechanisms Studies of Auricular Electroacupuncture on Hypothalamic P2Y1R in the Regulating Body Weight of db/db Mice(No.2021-q01)。

摘　　要：Brain injury due to intrauterine growth restriction(IUGR) is a thorny clinical problem that often leads to permanent neurological deficits such as cerebral palsy.Few practical therapies can treat an IUGR-associated brain injury.We employed acupuncture to treat a 6-month-old male patient with severe hypoxic-ischemic encephalopathy(HIE) due to IUGR,as confirmed by magnetic resonance imaging(MRI).Three courses of acupuncture treatment significantly improved some of the patient’s clinical characteristics,such as his insensitive responsiveness and motor deficits,with remarkably reversed HIE features on MRI at 1-year of age.This case suggests that acupuncture is a potential treatment option for an IUGRassociated brain injury and warrants further investigation.

关 键 词：ACUPUNCTURE fetal growth retardation brain injuries HYPOXIA-ISCHEMIA BRAIN magnetic resonance imaging neuronal plasticity 

分 类 号：R246[医药卫生—针灸推拿学]