微脉冲激光与传统激光治疗慢性中心性浆液性脉络膜视网膜病变疗效比较  

Comparison of curative effect between micropulse laser and traditional laser in the treatment of chronic central serous chorioretinopathy

作　　者：杨凯转[1] 闫淑[1] 杜敏[1] YANG Kaizhuan;YAN Shu;DU Min(Department of Ophthalmology,Zhengzhou Second Hospital,Zhengzhou 450000,Henan Province,China)

机构地区：[1]郑州市第二人民医院眼科,河南郑州450000

出　　处：《新乡医学院学报》2023年第7期644-647,652,共5页Journal of Xinxiang Medical University

摘　　要：目的比较微脉冲激光与传统激光治疗慢性中心性浆液性脉络膜视网膜病变(CSC)的临床效果。方法选择2020年6月至2021年6月郑州市第二人民医院收治的110例(110眼)慢性CSC患者为研究对象,根据治疗方法将患者分为微脉冲激光治疗组(n=60)和传统激光治疗组(n=50),2组患者均给予卵磷脂络合碘胶囊和益脉康分散片治疗,微脉冲激光治疗组患者在药物治疗基础上接受微脉冲激光治疗,传统激光治疗组患者在药物治疗基础上采用传统激光治疗。治疗前及治疗后1、3、6个月,检测所有患者的最佳矫正视力(BCVA)、视网膜下积液(SRF)高度及黄斑中心凹视网膜厚度(CRT)。治疗后6个月评估2组患者的临床疗效,并观察并发症发生情况。所有患者术后随访6~12个月,观察CSC复发情况。结果治疗前2组患者的BCVA、SRF高度及CRT比较差异无统计学意义(P>0.05),2组患者治疗后1、3、6个月BCVA、SRF高度及CRT显著低于治疗前(P<0.05);治疗后1个月,微脉冲激光治疗组患者的BCVA、SRF高度及CRT显著低于传统激光治疗组(P<0.05),治疗后3、6个月,2组患者的BCVA、SRF高度及CRT比较差异无统计学意义(P>0.05)。微脉冲激光治疗组和传统激光治疗组患者治疗总有效率分别为93.33%(56/60)、78.00%(39/60),微脉冲激光治疗组患者治疗总有效率显著高于传统激光治疗组(χ^(2)=5.445,P<0.05)。治疗后6个月内2组患者患眼均未出现激光治疗相关并发症;术后6~12个月,微脉冲激光治疗组和传统激光治疗组患者复发率分别为3.33%(2/60)、12.00%(6/50),2组患者复发率比较差异无统计学意义(χ^(2)=3.038,P>0.05)。结论与传统激光治疗相比,在药物治疗基础上,微脉冲激光治疗可以显著改善慢性CSC患者的BCVA、SRF和CRT,获得较好的临床效果,且未增加并发症和复发率。Objective To compare the clinical effect of micropulse laser and traditional laser in the treatment of chronic central serous chorioretinopathy(CSC).Methods A total of 110 patients(110 eyes)with chronic CSC admitted to Zhengzhou Second Hospital from June 2020 to June 2021 were selected as the study subjects,and the patients were divided into micropulse laser treatment group(n=60)and traditional laser treatment group(n=50)according to the treatment methods.The patients in the two groups were treated with lecithin complex iodine capsules and Yimaikang dispersible tablets.The patients in the micropulse laser treatment group received micropulse laser therapy on the basis of drug therapy,and the patients in the traditional laser treatment group received traditional laser therapy on the basis of drug therapy.The best corrected visual acuity(BCVA),subretinal fluid(SRF)height and retinal thickness of central retinal thickness(CRT)of all patients were detected before treatment and 1,3 and 6 months after treatment.The clinical curative effect of the patients in the two groups was evaluated at six months after treatment,and the complications was observed.All patients were followed up for 6-12 months to observe the recurrence of CSC.Results There was no significant difference in BCVA,SRF height and CRT between the two groups before treatment(P>0.05).The BCVA,SRF height,and CRT of patients in the two groups at 1,3,and 6 months after treatment were significantly lower than those before treatment(P<0.05).One month after treatment,the BCVA,SRF height and CRT of patients in the micropulse laser treatment group were significantly lower than those in the traditional laser treatment group(P<0.05).There was no significant difference in BCVA,SRF height and CRT between the two groups at 3 and 6 months after treatment(P>0.05).The total effective rate of patients in the micropulse laser treatment group and the traditional laser treatment group was 93.33%(56/60)and 78.00%(39/60),respectively.The total effective rate of patients in the mic

关 键 词：慢性中心性浆液性脉络膜视网膜病变 微脉冲激光 传统激光 视力 视网膜下积液 

分 类 号：R774.5[医药卫生—眼科]