Irreversible electroporation of the pancreas-A decade on  

作　　者：Daniel Yuxuan Ong Guo Yuan How Uei Pua 

机构地区：[1]Department of Diagnostic Radiology,Tan Tock Seng Hospital,Singapore

出　　处：《Journal of Interventional Medicine》2023年第1期10-13,共4页介入医学杂志（英文）

摘　　要：Irreversible electroporation(IRE) employs the use of an electric field to cause irreversible permeability of the cell membrane, inducing apoptosis. The use of IRE for locally advanced pancreatic cancer(LAPC) was first described in 2012. The crucial advantage of IRE compared with other devices employing thermal ablation is the safety around vital structures such as vessels and ducts. This makes it an attractive option for use in the pancreas due to the close proximity of multiple major vascular structures, biliary ducts, and adjacent gastrointestinal organs. Over the past decade, IRE has established itself as a useful treatment adjunct and may soon become the standard of care, particularly for LAPC. This article will explore the current evidence and provide a concise summary of pertinent issues, including patient selection, preoperative management, clinical outcomes, radiological response and future prospects of IRE in pancreatic cancer.

关 键 词：IRREVERSIBLE ELECTROPORATION PANCREATIC Cancer PANCREAS 

分 类 号：R735.9[医药卫生—肿瘤]