胸腹腔镜联合颈胸腹三切口食管癌根治颈部吻合术治疗食管癌的临床效果  

Clinical Effect of Thoracic Laparoscopy Combined with Cervical Thoracoabdominal Three-incision Radical Treatment of Esophageal Cancer and Cervical Anastomosis in the Treatment of Esophageal Cancer

作　　者：黄灿华 蔡华新 HUANG Canhua;CAI Huaxin(Nan’an Hospital,Nan’an 362300,China;不详)

机构地区：[1]南安市医院,福建南安362300

出　　处：《中外医学研究》2023年第17期19-22,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨胸腹腔镜联合颈胸腹三切口食管癌根治颈部吻合术治疗食管癌的临床效果。方法:选取2019年3月—2022年6月南安市医院胸外科收治的62例食管癌患者为研究对象。根据随机数表法将其划分为对照组和观察组,各31例。对照组予以颈胸腹三切口食管癌根治颈部吻合术治疗,观察组予以胸腹腔镜联合颈胸腹三切口食管癌根治颈部吻合术治疗。比较两组围手术期指标,术前及术后3 d炎症因子、免疫功能,并发症。结果:观察组淋巴结清扫数目多于对照组,术中出血量、术后引流量均少于对照组,手术操作时间、术后引流时间和住院时间均短于对照组,差异有统计学意义(P<0.05)。术后3 d,观察组白细胞介素-6、白细胞介素-8水平均低于对照组,差异有统计学意义(P<0.05)。术后3 d,观察组CD4^(+)高于对照组,CD8^(+)低于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率为6.45%,低于对照组的25.81%,差异有统计学意义(P<0.05)。结论:给予食管癌患者胸腹腔镜联合颈胸腹三切口食管癌根治颈部吻合术治疗,手术操作时间短、出血量少,能够促进机体术后快速恢复,有效改善机体炎症因子水平和免疫功能,并减少并发症的发生。Objective:To investigate the clinical effect of thoracic laparoscopy combined with cervical thoracoabdominal threeincision radical treatment of esophageal cancer and cervical anastomosis in the treatment of esophageal cancer.Method:A total of 62 patients with esophageal cancer admitted to the Department of Thoracic Surgery of Nan’an Hospital from March 2019 to June 2022 were selected as the study objects.They were divided into control group and observation group according to random number table method,31 cases in each group.The control group was treated with cervical thoracoabdominal three-incision radical treatment of esophageal cancer and cervical anastomosis,while the observation group was treated with thoracic laparoscopy combined with cervical thoracoabdominal threeincision radical treatment of esophageal cancer and cervical anastomosis.Perioperative indexes,inflammatory factors,immune function before and 3 d after surgery and complications were compared between the two groups.Result:The number of lymph node dissection in the observation group was more than that in the control group,the amount of intraoperative blood loss and postoperative drainage volume were less than those in the control group,and the operation time,postoperative drainage time and hospital stay were shorter than those in the control group,with statistical significance(P<0.05).At 3 d after surgery,the levels of interleukin-6 and interleukin-8 in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).At 3 d after surgery,CD4^(+) in the observation group was higher than that in control group,and CD8^(+) was lower than that in the control group,the differences were statistically significant(P<0.05).The incidence of complications in the observation group was 6.45%,which was lower than 25.81%in the control group,and the difference was statistically significant(P<0.05).Conclusion:Patients with esophageal cancer are treated with thoracic laparoscopy combined with cervical thor

关 键 词：食管癌 食管癌根治颈部吻合术 胸腹腔镜 颈胸腹三切口 炎症因子 免疫功能 

分 类 号：R735.1[医药卫生—肿瘤]