生物陶瓷仿生矿化牙釉质研究进展  

Research Progress of Biomimetic Mineralization Enamel Using Bioactive Ceramics

作　　者：王羽 董志红 李佳瑶 程丽佳[2] 唐璐[3] 宋巧钰 WANG Yu;DONG Zhihong;LI Jiayao;CHENG Lijia;TANG Lu;SONG Qiaoyu(School of Mechanical Engineering,Chengdu University,Chengdu 610106,China;School of Preclinical Medicine,Chengdu University,Chengdu 610106,China;Affiliated Hospital,Chengdu University,Chengdu 610081,China)

机构地区：[1]成都大学机械工程学院,四川成都610106 [2]成都大学基础医学院,四川成都610106 [3]成都大学附属医院,四川成都610081

出　　处：《成都大学学报（自然科学版）》2023年第2期125-131,138,共8页Journal of Chengdu University（Natural Science Edition）

基　　金：成都市科技局技术创新研发项目(2021-YF05-01871-SN);成都市卫健委医学科研项目(2021059)。

摘　　要：牙齿脱矿及时修复,可避免龋齿的发生,尤其是儿童牙齿矿化不全,更容易导致脱矿而引起龋齿.生物医用活性陶瓷具有较好的生物活性和生物诱导性,可促进组织的矿化.通过钙磷基和钙硅基生物活性陶瓷探讨对牙釉质脱矿后的仿生矿化效果,对比其矿化机制进行阐述.该类生物活性陶瓷具有较好的生物学性能,在口腔及骨修复中发展前景较好,是临床上硬组织修复的首选材料之一.The timely tooth demineralization repair can avoid the occurrence of dental caries.In particular,children′s teeth mineralization is not complete,which is more likely to lead to demineralization and further cause dental caries.Bioactive ceramics have good bioactivity and bio-inducibility so that they can promote the mineralization of tissues.In this study,the bionic remineralization effect of demineralized enamel was discussed by calcium phosphorus-based and calcium-silicon-based bioactive ceramics,and their mineralization mechanism was elaborated in detail.This type of bioactive ceramic has good biological properties and good development prospects in oral and bone restoration and is one of the preferred as hard tissue repair matrials for clinic.

关 键 词：生物陶瓷 仿生矿化 牙釉质 研究进展 

分 类 号：R781.1[医药卫生—口腔医学] TQ174.1[医药卫生—临床医学]