壳聚糖基生物材料在骨肉瘤治疗中的相关应用进展  

Progress in the Application of Chitosan Based Biomaterials in the Treatment of Osteosarcoma

作　　者：刘煜华 王艳华[1] Liu Yuhua;Wang Yanhua(Department of Pathology,College of Basic Medical Sciences,China Three Gorges University,Yichang 443002,China)

机构地区：[1]三峡大学基础医学院病理学系,湖北宜昌443002

出　　处：《巴楚医学》2023年第2期118-123,共6页Bachu Medical Journal

基　　金：国家自然科学基金项目(No:81602559)。

摘　　要：骨肉瘤是一种恶性原发性骨肿瘤,起源于有成骨潜能的间叶细胞,常见于青春期的少年和儿童,严重影响青少年的身心健康。壳聚糖是甲壳素衍生的天然聚合物,作为药物载体,在治疗骨肉瘤方面具备良好的优势和应用前景。本文拟就壳聚糖基生物材料在骨肉瘤治疗中的相关应用进展作一综述。Osteosarcoma is a malignant primary bone tumor that originates from mesenchymal cells with osteogenic potential,which is common in adolescents and children,seriously affects the physical and mental health.Chitosan is a natural polymer derived from chitin.As a drug carrier,chitosan has good advantages and application prospects in the treatment of osteosarcoma.This article aims to review the relevant application of chitosan based biomaterials in the treatment of osteosarcoma.

关 键 词：骨肉瘤 壳聚糖 生物材料 

分 类 号：R738.1[医药卫生—肿瘤]