空间多组学测序为组织原位的转录调控研究提供新的机遇  

Spatial multi-omics co-sequencing provides new opportunity for in situ transcriptional regulation study

作　　者：林立惠 蔡佺佑 陈捷凯 Lihui Lin;Quanyou Cai;Jiekai Chen(CAS Key Laboratory of Regenerative Biology,Centre for Cell Lineage and Development,Guangzhou Institutes of Biomedicine and Health,Chinese Academy of Sciences(CAS),Guangzhou 510530,China)

机构地区：[1]CAS Key Laboratory of Regenerative Biology,Centre for Cell Lineage and Development,Guangzhou Institutes of Biomedicine and Health,Chinese Academy of Sciences(CAS)

出　　处：《Science Bulletin》2023年第10期969-971,M0003,共4页科学通报（英文版）

摘　　要：Spatial techniques can profile omics information while preserving the spatial coordinates of tissues.Compared with single-cell sequencing,the additional spatial information is vital in studying the intercellular communication underlying development and disease[1].In the past,spatial techniques can only capture one layer of omics at a time,such as transcriptome[2],epigenome[3–5]。

关 键 词：PRESERVING INTERCELLULAR COORDINATES 

分 类 号：Q811.4[生物学—生物工程]