Awakening of ancient retrovirus:a new sign of aging in humans?  

作　　者：Yuliang Qu Jichang Wang 

机构地区：[1]Department of histology and embryology,Zhongshan School of Medicine,Sun Yat-sen University,Guangzhou,510080,China [2]Key Laboratory for Stem Cells and Tissue Engineering(Sun Yat-sen University),Ministry of Education,Guangzhou,510080,China

出　　处：《Science China(Life Sciences)》2023年第6期1454-1455,共2页中国科学（生命科学英文版）

摘　　要：Endogenous retroviruses(ERVs)are viral elements that have been incorporated into the host genomes of mammals over time and have evolved to become part of the host genome.Some ERVs have been domesticated and serve a role in host development and health.HML-2,a recently integrated family of human endogenous retrovirus K(HERVK)(Garcia-Montojo et al.,2018),is an example of such ERVs and is transcribed during early human development to encode viral proteins that are proposed to promote antiviral immune response and specialization of primordial germ cells(Grow et al.,2015;Xiang et al.,2022).

关 键 词：ENDOGENOUS AGING 

分 类 号：R346[医药卫生—基础医学]