浸润深度与口底鳞状细胞癌颈淋巴转移的相关性研究  

Correlation between the depth of invasion and cervical metastasis of squamous cell carcinoma of mouth foor

作　　者：周传清 张千骥 张福胤[1] 孙波[1] 隋馥勇 ZHOU Chuanqing;ZHANG Qianji;ZHANG Fuyin;SUN Bo;SUI Fuyong(Department of Oral and Maxillofacial Surgery,The Second Affiliated Hospital of Dalian Medical University,China,116027)

机构地区：[1]大连医科大学附属第二医院口腔颌面外科,116027

出　　处：《实用口腔医学杂志》2023年第3期364-367,共4页Journal of Practical Stomatology

摘　　要：目的:探究浸润深度(DOI)与口底鳞癌颈淋巴转移之间的相关性,并确定DOI预测早期口底鳞癌颈淋巴转移的最佳截止值。方法:收集30例口底鳞状细胞癌患者的临床资料,包括年龄、性别及颈淋巴转移情况,并调阅患者病理玻片,测量肿瘤原发灶DOI,对所得数据进行统计学分析。结果:DOI≤5mm组转移率为14.3%,5mm<DOI≤10mm组转移率为50.0%,DOI>10mm组转移率为87.5%,经Fisher精确检验,P=0.002(<0.05),通过ROC曲线统计分析,确定DOI预测早期口底鳞癌颈淋巴转移的最佳截止值为5.5mm。结论:DOI和口底鳞癌颈淋巴转移之间具有显著相关性,DOI预测早期口底鳞癌颈淋巴转移的最佳截止值为5.5mm。Objective:To explore the correlation between the depth of invasion(DOI)and cervical metastasis of squamous cell carcinoma(SCC)of mouth foor and to explore the cut-off value of DOI for predicting cervical metastasis in the patients with early SCC of mouth foor.Methods:The clinical data of 30 cases of SCC of mouth foor,including age,gender and cervical metastasis were collected.The DOI was measured by review of the pathological slides of the patients.Results:The cervical metastasis rate was 14.3%in the DOI≤5 mm group,50.0%in the 5 mm<DOI≤10 mm group,and 87.5%in the DOI>10 mm group.Fisher's exact test showed P=0.002.The cut-off value 5.5 mm of DOI for predicting cervical metastasis in early SCC of mouth foor was obtained by the analysis of receiver operating characteristic curve(ROC).Conclusion:There is a significant correlation between DOI and cervical metastasis of SCC of mouth foor.The cut-off value of DOI for predicting cervical metastasis in early SCC of mouth foor is 5.5 mm.

关 键 词：口底鳞状细胞癌 浸润深度 颈淋巴转移 最佳截止值 

分 类 号：R739.8[医药卫生—肿瘤]