植物还原制备纳米金过程中黄酮类物质的作用、外界影响因素及其应用  

Role of Flavonoids and External Influencing Factors in the Process of Preparing Nano-gold by Plant Reduction and Its Application

作　　者：刘海[1,2,3] 王飞[1,2,3] 王毅敏[1,2,3] 宋桃 柯义虎 LIU Hai;WANG Fei;WANG Yi-min;SONG Tao;KE Yi-hu(School of Chemistry and Chemical Engineering,North Minzu University,Yinchuan 750021,China;Key Laboratory for Chemical Engineering and Technology,State Ethnic Affairs Commission,North Minzu University,Yinchuan 750021,China;Ningxia Key Laboratory of Solar Chemical Conversion Technology,North Minzu University,Yinchuan 750021,China)

机构地区：[1]北方民族大学化学与化学工程学院,宁夏银川750021 [2]北方民族大学国家民委化工技术基础重点实验室,宁夏银川750021 [3]北方民族大学宁夏太阳能化学转化技术重点实验室,宁夏银川750021

出　　处：《化学试剂》2023年第7期78-86,共9页Chemical Reagents

基　　金：宁夏自然科学基金项目(2021AAC03200);宁夏高等学校科学研究项目(NXG2020055)。

摘　　要：植物还原法制备纳米金(Gold nanoparticles, GNPs)绿色经济、易操作、原材料可再生,避免了有毒化学试剂的使用以及物理法高成本的投入,为GNPs的制备提供了新的途径。然而,植物种类繁多且生物成分复杂,以植物提取液为整体制备GNPs不同的活性组分会互相干扰,使GNPs合成机制变得复杂。此外,提取液与金前体浓度、酸碱度、温度等外界因素也直接影响着GNPs的合成。系统的综述了黄酮类物质在合成GNPs过程中的还原与保护机理,外界因素在转化率、形貌粒径、分散性等方面的影响规律以及GNPs在抗癌,药物传递,抗菌,催化等领域的应用,最后展望了植物法制备GNPs的局限性。对调控制备GNPs活性组分的作用机制以及制备条件的优化具有指导意义。The preparation of gold nanoparticles(GNPs)by plant reduction method is green,economical,easy to operate,and the raw materials are renewable.It avoids the use of toxic chemical reagents and the high cost of physical methods,and provides a new way for the preparation of GNPs.However,there are many kinds of plants and complex biological components.When the plant extract is used as a whole to prepare GNPs,different active components will interfere with each other,leading to the synthetic mechanism of GNPs complicated.In addition,the concentration of extract and the gold precursor,pH value,temperature and other external factors also directly affect the synthesis of GNPs.The reduction and protection mechanism of flavonoids in the process of synthesizing GNPs,the influence law of external factors in conversion rate,morphology,particle size and dispersion,and the application of GNPs in anticancer,drug delivery,antibacterial and catalysis were systematically reviewed.Finally,the limitations of preparing GNPs by plant method were prospected.It would provide significant guidance for regulating the action mechanism of active components for preparing GNPs and optimizing the preparation conditions.

关 键 词：植物还原法 纳米金 黄酮类物质 外界因素 应用 

分 类 号：Q501[生物学—生物化学]