颌骨Gorham-Stout病1例及文献复习  

Gorham-Stout disease in maxillofacial bone:a case report and literature review

作　　者：吴一凡[1] 卢浩 刘胜文[1] 徐万林 杨雯君[1] Wu Yifan;Lu Hao;Liu Shengwen;Xu Wanlin;Yang Wenjun(Dept.of Oral and Maxillofacial-Head and Neck Oncology,Shanghai Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine,College of Stomatology,Shanghai Jiao Tong University,National Center for Stomatology,National Clinical Research Center for Oral Diseases,Shanghai Key Laboratory of Stomatology,Shanghai 200011,China)

机构地区：[1]上海交通大学医学院附属第九人民医院口腔颌面-头颈肿瘤科、上海交通大学口腔医学院、国家口腔医学中心、国家口腔疾病临床医学研究中心、上海市口腔医学重点实验室,上海200011

出　　处：《国际口腔医学杂志》2023年第4期445-451,共7页International Journal of Stomatology

基　　金：上海市青年科技英才扬帆计划(21YF1423500,20YF142-3300);上海第九人民医院生物样本库项目(YBKB202214)。

摘　　要：Gorham-Stout病(GSD)又名大块骨溶解症或消失性骨病(VBD),是一种以淋巴组织及血管增生为主要病理特点的自发性、进行性的骨吸收疾病。该病没有年龄、性别及种族差异,可累及全身单个或多个骨骼,罕发于颌面部。目前,GSD的发病原因尚存争议,其治疗方案及疗效的评价仍未达成统一的标准。本文通过报道1例上海交通大学医学院附属第九人民医院口腔颌面-头颈肿瘤科收治的骨溶解症病例,结合国内外相关文献,对GSD的病因、临床病理特点、诊断要点及治疗作一综述,以进一步提高对发生于颌骨的GSD的认识。Gorham-Stout disease(GSD),also known as massive osteolysis or vanishing bone disease(VBD),is a spontaneous,progressive disease of bone resorption characterized by lymphoid tissue and vascular hyperplasia.GSD does not differ in age,sex,or race and can involve single or multiple bones,but rarely occurs in the maxillofacial region.However,its cause remains controversial,and there is still no unified standard for the evaluation of treatment options and efficacy.In this paper,we report a case of GSD with recurrence in the Department of Oral and Maxillofacial-Head and Neck Oncology,Shanghai Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine.In addition,we briefly review the etiology,clinicopathological features,diagnostic points,and treatment of GSD to further enhance our understanding of GSD that occurs in the maxillofacial bone.

关 键 词：Gorham-Stout病 骨溶解症 消失性骨病 颌面骨 

分 类 号：R782[医药卫生—口腔医学]