高精度经颅直流电刺激治疗脑高级功能障碍的研究进展  

Research progress on high-definition transcranial direct current stimulation in the treatment of advanced brain dysfunction

作　　者：张双双 张劼 童奇峰 叶祥明[2] Zhang Shuangshuang;Zhang Jie;Tong Qifeng;Ye Xiangming(Graduate School,Bengbu Medical University,Bengbu 233030,China;Department of Rehabilitation,Zhejiang Provincial People's Hospital,Hangzhou 310014,China;The Second Clinical Medical College,Zhejiang Chinese Medical University,Hangzhou 310053,China)

机构地区：[1]蚌埠医学院研究生院,233030 [2]浙江省人民医院康复医学科,杭州310014 [3]浙江中医药大学第二临床医学院,杭州310053

出　　处：《神经疾病与精神卫生》2023年第6期451-456,共6页Journal of Neuroscience and Mental Health

基　　金：浙江省自然科学基金项目(LGF22H170003,LGF20H170011)。

摘　　要：中枢神经系统病变或损伤后常合并脑高级功能障碍,部分患者单药物治疗效果不佳,因此迫切需要新的治疗方式辅助药物治疗。高精度经颅直流电刺激作为一种新型的神经康复技术,通过特别设计的高精度电极以低强度的电流作用于特定的脑区,调节大脑皮层神经活动。目前,高精度经颅直流电刺激对于卒中后失语、意识障碍、抑郁症、癫痫后认知障碍等脑高级功能障碍疾病有不同程度的改善。本文从作用原理及机制为切入点,结合国内外研究成果,概述高精度经颅直流电刺激相关研究及其在脑高级功能障碍中的临床应用,旨在对未来的发展提供依据。Central nervous system lesions or injuries are often associated with advanced brain dysfunction,and some patients have poor efficacy in monotherapy.Therefore,there is an urgent need for new treatment methods to assist drug therapy.As a new type of neural rehabilitation technology,high-definition transcranial direct current stimulation regulates the neural activity of the cerebral cortex by acting on specific brain regions with low-intensity current through specially designed high-precision electrodes.At present,highdefinition transcranial direct current stimulation has shown varying degrees of improvement in post-stroke aphasia,disturbance of consciousness,depression,cognitive impairment after epilepsy and other advanced brain dysfunction diseases.This article takes the principle and mechanism of action as the starting point,and combines domestic and foreign research results to summarize the research on high-precision transcranial direct current stimulation and its clinical application in advanced brain dysfunction,aiming to provide a basis for future development.

关 键 词：高精度经颅直流电刺激 脑高级功能障碍 神经康复 综述 

分 类 号：R741.05[医药卫生—神经病学与精神病学]