非钠离子快速纠正的脑桥中央髓鞘溶解的临床分析  

A clinical analysis of central pontine myelinolysis not caused by rapid correction of sodium ion abnormalities

作　　者：王旭锋 彭永 甘棋心 唐艳丹 李拥军 张镇群 WANG Xufeng;PENG Yong;GAN Qixin;TANG Yandan;LI Yongjun;ZHANG Zhenqun(Provincial Traditional Chinese Medicine Hospital of Hunan University of Traditional Chinese Medicine,Zhuzhou,Hunan 412000,China;Department of Neurology,Affiliated First Hospital of Hunan Traditional Chinese Medical College,Zhuzhou,Hunan 412000,China;Department of Radiology,Affiliated First Hospital of Hunan Traditional Chinese Medical College,Zhuzhou,Hunan 412000,China)

机构地区：[1]湖南中医药大学附属省直中医医院,湖南株洲412000 [2]湖南中医药高等专科学校附属第一医院神经内科,湖南株洲412000 [3]湖南中医药高等专科学校附属第一医院放射科,湖南株洲412000

出　　处：《国际神经病学神经外科学杂志》2023年第2期49-52,共4页Journal of International Neurology and Neurosurgery

基　　金：湖南省中医药管理局重点课题(201915);湖南省卫计委课题(B20180815);湖南中医药高等专科学校附属第一医院优秀科研创新团队(B2021-003);株洲市科技计划项目(2021-009,2021/01–2023/12)。

摘　　要：脑桥中央髓鞘溶解(central pontine myelinolysis,CPM)是一种临床较为罕见的疾病,通常导致该病的原因是钠离子异常的快速纠正。该文报道了3例并非由钠离子快速纠正导致的CPM,其中2例为极高血糖并酮症酸中毒引起的,1例为钾离子过低引起的。经过治疗原发病和营养脑神经后,患者均好转出院。该文总结了这3个病例的临床特点,同时总结分析了国内外CPM相关的研究进展,希望能提高对于该病的认识。Central pontine myelinolysis(CPM) is a relatively rare disease in clinical practice and is often caused by the rapid correction of sodium ion abnormalities.This article reports three cases of CPM not caused by the rapid correction of sodium ion abnormalities,among which two cases were caused by extremely high blood glucose and ketoacidosis and one case was caused by low potassium ion.All patients were improved and discharged after the treatment of primary diseases and the nutrition of brain nerves.This article summarizes the features of these three cases and reviews related research advances in CPM,so as to improve the awareness of this disease.

关 键 词：脑桥中央髓鞘溶解症 钾离子异常 糖尿病酮症酸中毒 

分 类 号：R744.5[医药卫生—神经病学与精神病学]