全腔镜下四孔单向式解剖性肺叶切除术治疗早期非小细胞肺癌患者的临床疗效分析  

Clinical Analysis of Four-hole Unilateral Anatomical Lobectomy Under Total Endoscopy for Early Non-small Cell Lung Cancer

作　　者：袁庆[1] 宋瑞娟[1] 姚丹丹 YUAN Qing;SONG Ruijuan;YAO Dandan(Henan Cancer Hospital,Zhengzhou,450003)

机构地区：[1]河南省肿瘤医院,450003

出　　处：《实用癌症杂志》2023年第7期1136-1138,共3页The Practical Journal of Cancer

摘　　要：目的探讨全腔镜下四孔单向式解剖性肺叶切除术对早期非小细胞肺癌(NSCLC)患者的疗效。方法选取92例早期NSCLC患者,按随机数字表法分为两组,各46例。两组均在全腔镜下进行手术,对照组予以三孔解剖性肺叶切除术,观察组则施行四孔单向式手术,观察至术后6个月。对比两组手术相关指标、疼痛程度、并发症、生活质量。结果观察组术中出血量较对照组少,手术时间、住院时间较对照组短,并发症发生率较对照组低,有统计学差异(P<0.05);术后1、3 d,观察组的视觉模拟疼痛量表(VAS)评分较对照组低,有统计学差异(P<0.05);术前两组的生活质量综合评定问卷(GQOLI-74)内心理、躯体、社会功能与物质状态评分相比,无统计学差异(P>0.05);术后观察组各项维度评分均较对照组高,有统计学差异(P<0.05)。结论全腔镜下四孔单向式解剖性肺叶切除术在早期NSCLC患者治疗中效果确切,可显著缩减出血量,缩短术式操作时间,加快术后恢复,且并发症较少,有利于生活质量的提升。Objective To investigate the effect of total endoscopic four-hole unilateral anatomical lobectomy on patients with early non-small cell lung cancer(NSCLC).Methods 92 patients with early NSCLC were selected and divided into 2 groups according to random number table,46 patients in each group.The 2 groups were operated under total endoscopy,the control group was performed with three-hole anatomical lobectomy,and the observation group was performed with four-hole one-way operation until 6 months after operation.The operation related indexes,pain degree,complications and quality of life were compared between the 2 groups.Results The amount of intraoperative bleeding in the observation group was less than that in the control group,the operation time and hospital stay were shorter than that in the control group,and the incidence of complications was lower than that in the control group,with a statistical difference(P<0.05);The score of visual analogue pain scale(VAS)in the observation group was lower than that in the control group at 1 and 3 days after operation,with statistical difference(P<0.05);There was no statistical difference in the scores of psychological,physical,social function and material state in the comprehensive quality of life assessment questionnaire(GQOLI-74)between the 2 groups before operation(P>0.05);After operation,the scores of each dimension in the observation group were higher than those in the control group,with statistical difference(P<0.05).Conclusion Total endoscopic four-hole one-way anatomical lobectomy is effective in the treatment of early NSCLC patients.It can significantly reduce the amount of bleeding,shorten the operation time,speed up postoperative recovery,and has fewer complications,which is conducive to the improvement of quality of life.

关 键 词：早期非小细胞肺癌 解剖性肺叶切除术 并发症 生活质量 

分 类 号：R734.2[医药卫生—肿瘤]