机器人Remebot辅助内囊前肢毁损术治疗伴精神障碍的脑性瘫痪儿童的疗效观察  

Clinical efficacy of robot Remebot-assisted lesioning of the anterior limb of the internal capsule for children with cerebral palsy associated with mental disorders

作　　者：惠瑞 吕彬 刘钰鹏 王川 刘清 李红玉 徐莉莉 田增民 HUI Rui;LU Bin;LIU Yu-peng;WANG Chuan;LIU Qing;LI Hong-yu;XU Li-li;TIAN Zeng-min(Department of Functional Neurosurgery,Shandong Taian Novel International Medical Center,Taian 271000,China)

机构地区：[1]诺莱国际医学中心功能神经外科,山东泰安271000

出　　处：《中国临床神经外科杂志》2023年第6期369-371,共3页Chinese Journal of Clinical Neurosurgery

基　　金：国家863计划资助项目(2007AA04Z246)。

摘　　要：目的探讨机器人Remebot辅助内囊前肢毁损术治疗伴精神障碍的脑性瘫痪儿童的疗效。方法回顾性分析2020年12月~2021年9月应用机器人Remebot辅助内囊前肢毁损术治疗的36例伴有精神障碍的脑性瘫痪儿童的临床资料。术前、术后1周、术后6个月采用Gesell发育商量表和粗大运动功能测试量表(GMFM-88)评估疗效。结果术后复查CT显示毁损范围均覆盖预定靶点,无颅内出血。术前Gesell/GMFM-88评分分别为126.5(71~236.3)分/65.1(41.2~87.4)分,术后1周分别为129(76.3~241.5)分/76.5(42.1~91.4)分,术后6月分别为132(75.8~223.8)分/76.6(42.8~93.8)分。术后1周、6个月Gesell/GMFM-88评分较术前均明显增高(P<0.05)。结论机器人辅助内囊前肢毁损术治疗伴精神障碍的脑性瘫痪儿童安全、可靠,除提高患儿的运动功能外,对精神障碍的改善也具有积极意义。Objective To investigate the effectiveness of robot Remebot-assisted lesioning of the anterior limb of the internal capsule for children with cerebral palsy associated with mental disorders.Methods The clinical data of 36 children with cerebral palsy associated with mental disorders who were treated with robot Remebot-assisted lesioning of the anterior limb of the internal capsule from December 2020 to September 2021 were analyzed retropsectively.Gesell Developmental Schedules and Gross Motor Function Measure(GMFM-88)scales were used to evaluate the development level and motor function before operation,1 week,and 6 months after operation.Results CT after operation showed that lesioning regions covered the target anterior limb of the internal capsule in all the patients,and there were no intracranial bleeding.The median preoperative Gesell/GMFM-88 scores were 126.5(71~236.3)and 65.1(41.2~87.4),respectively.The median Gesell/GMFM-88 scores were 129(76.3~241.5)and 76.5(42.1~91.4)1 week after operation,respectively.The median Gesell/GMFM-88 scores were 132(75.8~223.8)and 76.6(42.8,93.8)6 months after operation,respectively.The Gesell/GMFM-88 scores 1 week and 6 months after operation significantly increased compared with before operation(P<0.05).Conclusions Robot-assisted frameless stereotactic surgery is safe and reliable in the treatment of children with cerebral palsy associated with mental disorders.It not only improves the motor function of patients,but also has positive significance for the improvement of mental disorders.

关 键 词：脑性瘫痪 精神障碍 儿童 机器人Remebot 内囊前肢毁损术 

分 类 号：R742.3[医药卫生—神经病学与精神病学] R651.11[医药卫生—临床医学]