男男性行为人群甲型肝炎流行情况研究进展  

Advances on epidemiology of hepatitis A among men who have sex with men

作　　者：石腾飞 耿坤静 刘树芳[1] 耿彦生[1] SHI Tengfei;GENG Kunjing;LIU Shufang;GENG Yansheng(Key Laboratory of Public Health Safety of Hebei Province,School of Public Health,Hebei University,Baoding 071000,China)

机构地区：[1]河北大学公共卫生学院河北省公共卫生安全重点实验室,保定071000 [2]保定市传染病医院检验科,071000

出　　处：《传染病信息》2023年第3期267-271,共5页Infectious Disease Information

基　　金：河北省自然科学基金项目(2021201015)。

摘　　要：甲型肝炎(甲肝)是由甲肝病毒(hepatitis A virus,HAV)引起的急性病毒性肝炎,主要经粪-口途径传播。自20世纪末甲肝疫苗出现,全球不同国家和地区甲肝发病率大大降低。但近年欧洲许多国家和美洲、亚洲、大洋洲的一些国家或地区均发生甲肝暴发,主要发病的人群为男男性行为者(men who have sex with men,MSM),不同国家和地区MSM人群的HAV毒株存在关联,引起广泛关注。本文对甲肝在MSM人群中的流行情况进行综述,并探讨相关防控措施。Hepatitis A is an acute viral hepatitis caused by hepatitis A virus(HAV),which is mainly transmitted through fecal-oral route.Since the introduction of hepatitis A vaccine at the end of the 20th century,the global prevalence of hepatitis A has decreased.However,in recent years,hepatitis A outbreaks have occurred frequently in populations of men who have sex with men(MSM)in Europe,South America,North America,Asia,Oceania and other regions,and gene sequencing has revealed that HAV strains in different countries and regions are linked,causing widespread concern.This article reviews the prevalence of hepatitis A in MSM population and discusses the relevant prevention and control measures.

关 键 词：甲型肝炎 甲型肝炎病毒 男男性行为者 暴发 性传播疾病 性传播 基因型 传播途径 

分 类 号：R575.5[医药卫生—消化系统]