幽门螺杆菌与眼部疾病相关性研究进展  

Research progress on the correlation between Helicobacter pylori and ocular diseases

作　　者：薛愚愚 周琦 宿晓娟 叶河江[2] Yu-Yu Xue;Qi Zhou;Xiao-Juan Su;He-Jiang Ye(Chengdu University of Traditional Chinese Medicine,Chengdu 610072,Sichuan Province,China;Department of Ophthalmology,Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610075,Sichuan Province,China)

机构地区：[1]成都中医药大学,中国四川省成都市610072 [2]成都中医药大学附属医院眼科,中国四川省成都市610075

出　　处：《国际眼科杂志》2023年第7期1158-1162,共5页International Eye Science

基　　金：四川省中央引导地方科技发展专项项目(No.2021ZYD0095)。

摘　　要：幽门螺杆菌是一种常见的革兰氏阴性细菌,与多种消化系统疾病有关,如胃炎、十二指肠溃疡和胃癌等。近年来的研究显示幽门螺杆菌也和一些常见的眼科疾病有关,如中心性浆液性脉络膜视网膜病变、青光眼、前葡萄膜炎、眼附属器淋巴瘤等。幽门螺杆菌可能通过氧化损伤、循环障碍和免疫损伤等方式影响眼部疾病的病理生理过程。也有一些研究提示根除幽门螺杆菌对某些眼病有一定效果。本文对幽门螺杆菌在常见眼部疾病发生发展中的机制进行综述,深入探讨幽门螺杆菌与常见眼部疾病的关系可为有些眼病的预防或治疗提供新的思路。Helicobacter pylori is a common gram-negative bacterium,which is associated with a variety of gastroenteric diseases,such as gastritis,duodenal ulcer and gastric cancer.Recent studies suggested a potential role of Helicobacter pylori in the pathogenesis of common ocular diseases,such as central serous chorioretinopathy,glaucoma,anterior uveitis and ocular adnexal lymphoma.Helicobacter pylori might affect the pathophysiological process of ocular diseases through oxidative damage,circulatory disorders and immune injury.Some studies also suggested that eradication of Helicobacter pylori had certain effects on some ocular diseases.This review aims to summarize current evidence of the Helicobacter pylori in the pathogenesis of common ocular diseases,so as to encourage innovative approaches in the prevention and treatment of these ocular diseases.

关 键 词：幽门螺杆菌 中心性浆液性脉络膜视网膜病变 青光眼 前葡萄膜炎 眼附属器淋巴瘤 

分 类 号：R77[医药卫生—眼科]