不同MRI内淋巴囊分型对大前庭水管综合征患者ASNR的影响  

Effects of Different MRI Endolymphatic Sac Classification on ASNR Extraction Rate in Patients with Large Vestibular Aqueduct Syndrome

作　　者：王宇翔 王小林 韩跃峰[1] 朱慧慧 桑亚茹 张李娜 Wang Yuxiang;Wang Xiaolin;Han Yuefeng;Zhu Huihui;Sang Yaru;Zhang Lina(Department of Otorhinolaryngology,the First Affiliated Hospital of Bengbu Medical College,Bengbu,233000,China)

机构地区：[1]安徽省蚌埠市蚌埠医学院第一附属医院,蚌埠233000

出　　处：《听力学及言语疾病杂志》2023年第4期337-340,共4页Journal of Audiology and Speech Pathology

摘　　要：目的探究大前庭水管综合征(LVAS)患者MRI不同内淋巴囊分型对声诱发短潜伏期负反应(ASNR)的影响。方法回顾性分析26例(52耳)经影像学及临床综合诊断为LVAS患者的MRI T2WI及ABR资料,根据MRI内淋巴囊高低信号分布差异,分为Ⅰ型组8耳,Ⅱ型组12耳,Ⅲ型组32耳。并以经颞骨CT及内听道MRI确定无内耳畸形的重度-极重度感音神经性听力损失患者21例(42耳)作为对照组,比较各组ASNR引出率、反应阈及潜伏期。结果①LVAS组和对照组ASNR引出率分别为44.2%(23/52)和9.5%(4/42),差异有统计学意义(P<0.05);ASNR平均反应阈分别为91.57±7.25和89.25±6.99 dB nHL,差异无统计学意义(P>0.05);平均潜伏期分别为3.36±0.35和3.26±0.59 ms,差异无统计学意义(P>0.05)。②LVAS患者Ⅰ型组、Ⅱ型组和Ⅲ型组的ASNR引出率分别为50.0%(4/8)、33.3%(4/12)和46.7%(15/32),差异无统计学意义(P>0.05);ASNR平均反应阈分别为84.25±9.43、86.75±8.30和94.80±3.95 dB nHL,Ⅰ型组与Ⅲ型组之间差异有统计学意义(P<0.05);平均潜伏期分别为3.07±0.14、3.43±0.13和3.23±0.29 ms,差异无统计学意义(P>0.05)。结论LVAS患者ASNR引出率不受MRI内淋巴囊分型的影响,且较无内耳畸形的重度-极重度感音神经性聋患者更高。Objective To investigate the effect of different endolymphatic sac types of MRI on sound-induced short latency negative response(ASNR)in patients with large vestibular aqueduct syndrome(LVAS).Methods The data of MRI T2WI and brainstem evoked potential(ABR)of 26 patients(52 ears)with LVAS diagnosed by imaging and clinic were analyzed retrospectively.According to the difference of the distribution of high and low signals in the lymphatic sac of MRI,the patients were divided into typeⅠgroup(n=8),typeⅡgroup(n=12)and typeⅢgroup(n=32).Twenty-one patients(42 ears)with severe-profound sensorineural hearing loss without inner ear deformity confirmed by temporal bone CT and internal auditory canal MRI were used as control group.The induction rate,response threshold and latency of sound-induced short latency negative response(ASNR)were compared in each group.Results①The ASNR extraction rates of LVAS group and control group were 44.2%(23/52)and 9.5%(4/42)respectively,and the difference was statistically significant.The average response threshold score of ASNR was 91.57±7.25 dB nHL and 89.25±6.99 dB nHL,respectively,and the average latency was 3.36±0.35 ms and 3.26±0.59 ms,respectively.②The ASNR extraction rates of typeⅠgroup,typeⅡgroup and typeⅢgroup were 50.0%,33.3%and 46.7%,respectively,and there was no significant difference(P>0.05).The average reaction threshold of ASNR was 84.25±9.43,86.75±8.30,94.80±3.95 dB nHL respectively,and there was significant difference between typeⅠgroup and typeⅢgroup.The average latency was 3.07±0.14,3.43±0.13,3.23±0.29 ms,respectively,and there was no significant difference.Conclusion The ASNR extraction rate of LVAS patients was not affected by the classification of MRI endolymphatic sac,and it was higher than that of severe-profound sensorineural deafness without inner ear malformation.

关 键 词：大前庭水管综合征 声诱发短潜伏期负反应 MRI 内淋巴囊 

分 类 号：R764.73[医药卫生—耳鼻咽喉科]