分析BiPAP无创通气治疗重症难治性哮喘的临床价值  

Analysis of the Clinical Value of BiPAP Non-Invasive Ventilation in the Treatment of Severe Refractory Asthma

作　　者：林爽[1] 杨晓红[2] LIN Shuang;YANG Xiaohong(Xinjiang Medical University,Urumqi,Xinjiang Uygur Autonomous Region,830000 China;Department of Respiratory and Critical Care Medicine,People's Hospital of Xinjiang Uygur Autonomous Region,Urumqi,Xinjiang Uygur Autonomous Region,830000 China)

机构地区：[1]新疆医科大学,新疆乌鲁木齐830000 [2]新疆维吾尔自治区人民医院呼吸与危重症医学科,新疆乌鲁木齐830000

出　　处：《中外医疗》2023年第16期44-47,共4页China & Foreign Medical Treatment

基　　金：新疆维吾尔自治区自然科学基金(2022D01C312)。

摘　　要：目的分析对重症难治性哮喘患者通过采用双水平气道正压通气呼吸机(bilevel positive airway pressure ventilator,BiPAP)无创通气的治疗价值。方法方便选取2020年1月—2022年5月新疆维吾尔自治区人民医院呼吸与危重症医学科确诊为重症难治性哮喘患者72例,按照随机数表法分为对照组和观察组,各36例。对照组为常规治疗,观察组联合应用BiPAP无创通气治疗,对比两组治疗效果、血气分析指标、肺功能指标及生命体征指标。结果治疗后,观察组PaO_(2)、SaO_(2)、FEV1、PEF指标均较对照组更高,差异有统计学意义(P<0.05);治疗后,观察组PaCO_(2)、RR、HR、SBP较对照组更低,差异有统计学意义(P<0.05);观察组治疗总有效率为97.22%高于对照组的77.78%,差异有统计学意义(χ^(2)=4.571,P<0.05)。结论重症难治性哮喘患者应用BiPAP无创通气后其血气指标更优,肺功能均得以改善。Objective To analyze the therapeutic value of non-invasive ventilation with bilevel positive airway pressure ventilator(BiPAP)in patients with severe refractory asthma.Methods From January 2020 to May 2022,72 patients with severe and refractory asthma were conveniently selected from the Department of Respiratory and Critical Care Medicine of Xinjiang People's Hospital.They were divided into a control group and an observation group according to the random number table,with 36 cases in each group.The control group received routine treatment,while the observation group received a combination of BiPAP non-invasive ventilation treatment.The treatment effects,blood gas analysis indicators,lung function indicators,and vital signs indicators were compared between the two groups.Results After treatment,the PaO_(2),SaO_(2),FEV1,and PEF indicators in the observation group were higher than those in the control group,and the difference was statistically significant(P<0.05).After treatment,the PaCO_(2),RR,HR,and SBP in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05).The total effective rate of the observation group was 97.22%,which was higher than the control group's 77.78%,the difference was statistically significant(χ^(2)=4.571,P<0.05).Conclusion The index of blood gas and lung function of patients with severe refractory asthma were better,can be improved after BiPAP non-invasive ventilation.

关 键 词：难治性哮喘 重症医学 BIPAP无创通气 

分 类 号：R256.12[医药卫生—中医内科学]