防暑清热饮的质量控制  

Quality Control of Fangshu Qingre Mixture

作　　者：李杰 吴心怡 杨育儒 祝珊珊 秦飞 LI Jie;WU Xin-yi;YANG Yu-ru;ZHU Shan-shan;QIN Fei(Department of Pharmacy,Xiamen Medical College,Fujian Xiamen 361023;Department of Pharmacy,Southeast Hospital Affiliated to Xiamen University,Fujian Zhangzhou 363000,China)

机构地区：[1]厦门医学院药学系,福建厦门361023 [2]厦门大学附属东南医院药剂科,福建漳州363000

出　　处：《广州化工》2023年第7期103-106,共4页GuangZhou Chemical Industry

基　　金：福建省中青年教师教育科研项目(JAT210494);厦门医学院大学生创新创业训练计划项目(X202112631069);厦门医学院大学生创新创业训练计划资助项目(No:s202212631005)。

摘　　要：为建立防暑清热饮中总多酚和挥发性成分含量的测定方法,通过酒石酸亚铁法测定总多酚的含量,顶空气相色谱法测定薄荷酮、薄荷脑和百秋李醇的含量。结果总多酚、薄荷酮、薄荷脑和百秋李醇线性关系良好(r≥0.9991),平均加样回收率(RSD)分别为103.62%(2.33%)、90.29%(2.81%)、95.36%(3.49%)和90.20%(3.94%)。建立的测定方法简单、灵敏,能够准确测定该制剂中总多酚和挥发性指标成分的含量。A method for determination of total polyphenols and volatile components in Fangshu Qingre mixture was established.Total polyphenols were determined by ferrous tartrate method,menthone,menthol and patchouli alcohol were determined by headspace gas chromatography.The linear relationship between total polyphenols,menthone,menthol and patchouli alcohol was good(R≥0.9991),and the average recoveries(RSD)were 103.62%(2.33%),90.29%(2.81%),95.36%(3.49%)and 90.20%(3.94%),respectively.The method was simple,sensitive,and could accurately determine the contents of total polyphenols and volatile index components in the preparation.

关 键 词：防暑清热饮 总多酚 薄荷酮 薄荷脑 百秋李醇 顶空气相色谱法 

分 类 号：R284.1[医药卫生—中药学]