局部晚期宫颈癌自适应三维后装腔内放疗的危及器官影响  

ART-Three-dimensional effect on risk of organ volume for locally advanced cervical cancer

作　　者：王金云 王明慧 王盈 胡格 崔相利 WANG Jingyun;WANG Minghui;WANG Ying;HU Ge;CUI Xiangli(Department of Genitourinary Tumor Radiotherapy,Chinese Academy of Sciences Hefei Cancer Hospital,Hefei,Anhui,230000,China)

机构地区：[1]中国科学院合肥肿瘤医院泌尿生殖肿瘤放疗科,安徽合肥230000

出　　处：《当代医学》2022年第33期60-62,共3页Contemporary Medicine

摘　　要：目的探讨自适应三维后装腔内放疗与常规三维后装放疗治疗局部晚期宫颈癌危及器官的影响。方法选取2019年8月至2020年3月本院收治的32例局部晚期宫颈癌患者作为研究对象,所有患者均先接受45~50 Gy三维调强外照射,之后开始行后装治疗。分别采集每位患者每次三维后装CT扫描图像勾画靶区,根据病情需要制订多次治疗计划并实施。实际照射计划作为Pn组,按第一次计划假定完成全程后装组作为P1组,比较P1组及Pn组靶区受照射剂量、危及器官受照剂量学。结果Pn组HR-CTVD100及HR-CTVD90与P1组比较差异均无统计学意义。Pn组膀胱照射剂量和乙状结肠照射剂量与P1组比较差异均无统计学意义,Pn组直肠照射剂量低于P1组,差异有统计学意义(P<0.05)。结论自适应三维后装放疗可明显减少直肠的受照射剂量。Objective To explore the effect on risk of organ volume for locally advanced cervical cancer.Methods 32 patients with locally advanced cervical cancer admitted to our hospital from August 2019 to March 2020 were selected as research subjects,all patients received 45-50 Gy three-dimensional intensity modulated external irradiation first,and then began retrofitting therapy.Collected each patient CT scanning images then draw the plan according to the clinncal needs.The actual irradiation plan was named as Pn,and the plan processed as the first plan as P1 group.The difference of dose of target area and the volume of organs exposed to irradiation was compared between Pn group and P1 group.Results There was no significant difference in HR-CTVD100 and HR-CTVD90 between Pn group and P1 group.There was no statistical significance in bladder irradiation dose and sigmoid irradiation dose between Pn group and P1 group,and rectal irradiation dose in Pn group was lower than that in P1 group,the difference was statistically significant(P<0.05).Conclusion ART-three-dimensional brachytherapy could reduce the irradiated dose of rectal tissue.

关 键 词：局部晚期宫颈癌 自适应三维后装腔内放疗 直肠组织受量 

分 类 号：R737.33[医药卫生—肿瘤]