新疆地区胃肠道肿瘤患者维生素水平的流行病学调查  

An epidemiological survey of vitamin levels in patients with gastrointestinal tumors in Xinjiang

作　　者：马蕾[1] 韩忠诚[1] 柳江[1] MA Lei;HAN Zhongcheng;LIU Jiang(Department of Oncology,Xinjiang Uiger Municipal People’s Hospital,Xinjiang,Urumqi 830001,China)

机构地区：[1]新疆维吾尔自治区人民医院肿瘤科,乌鲁木齐市830001

出　　处：《河北医药》2023年第12期1892-1897,共6页Hebei Medical Journal

基　　金：吴阶平医学基金会临床科研专项资助基金(编号:320.6750.19088-41)。

摘　　要：目的探讨新疆地区胃肠道肿瘤患者维生素水平的流行病学特点,为临床制定防治措施提供依据。方法选取2020年5月至2021年5月新疆3个地区(乌鲁木齐、伊犁、喀什)胃肠道恶性肿瘤患者400例作为观察组,采用问卷调查、物理测量法统计患者信息资料,同期按1∶1比例选取新疆某健康体检中心健康体检者400例作为对照组,比较2组维生素水平,分析胃肠道肿瘤患者维生素缺乏的流行病学特征。结果400例胃肠道恶性肿瘤患者中维生素A缺乏占比30.25%,维生素D缺乏占比71.50%;不同年龄、饮酒情况、工作类型、糖尿病史、胃肠道肿瘤类型、TNM分期患者间维生素A水平比较,差异有统计学意义(P<0.05);不同年龄、性别、体重指数(body mass index,BMI)、腰臀比(waist-hip ratio,WHR)、女性绝经史、饮酒情况、工作类型、运动频率、心脑血管病史、糖尿病史、胃肠道肿瘤类型、TNM分期患者维生素D水平比较,差异有统计学意义(P<0.05);经Logistic回归模型分析,年龄、饮酒情况、胃肠道肿瘤类型、TNM分期均是胃肠道肿瘤患者维生素A缺乏的相关因素(P<0.05);年龄、性别、女性绝经史、饮酒情况、胃肠道肿瘤类型、TNM分期是胃肠道肿瘤患者维生素D缺乏的相关因素(P<0.05)。结论新疆地区胃肠道肿瘤患者受年龄、生活习惯等多种因素影响,维生素A、维生素D缺乏情况严峻,临床在治疗中需结合上述影响因素注重胃肠道肿瘤患者维生素A、维生素D的补充。Objective To explore the epidemiological characteristics of vitamin levels in patients with gastrointestinal tumors in Xinjiang,thus providing a basis for formulating prevention and treatment measures.Methods A total of 400 patients with gastrointestinal malignancies in 3 regions of Xinjiang(Urumqi,Yili,Kashgar)from May 2020 to May 2021 were selected as the research objects.Questionnaire surveys and physical measurement methods were used to collect patient information.During the same period,400 healthy volunteers receiving physical examinations in a health examination center in Xinjiang were selected as the control group at a ratio of 1∶1.The vitamin levels were compared between the two groups.The epidemiological characteristics of vitamin deficiency in patients with gastrointestinal tumors were analyzed.Results Among 400 patients with gastrointestinal malignant tumors,the incidence of vitamin A and D deficiency was 30.25%,and 71.50%,respectively.There were significant differences in vitamin A levels among patients with different ages,drinking status,type of work,history of diabetes,pathological type and tumor node metastasis(TNM)staging of gastrointestinal tumors(P<0.05).There were significant differences in vitamin D levels among patients with different ages,genders,body mass index(BMI),waist-to-hip ratio(WHR),menopausal history,drinking status,type of work,exercise frequency,history of cardiovascular and cerebrovascular diseases,history of diabetes,pathological type and TNM staging of gastrointestinal tumors(P<0.05).The logistic regression model analysis showed that age,drinking status,pathological type and TNM staging of gastrointestinal tumors were risk factors for vitamin A deficiency in patients with gastrointestinal tumors in Xinjiang(P<0.05).Age,gender,history of female menopause,alcohol consumption,pathological type and TNM staging of gastrointestinal tumors were risk factors for vitamin D deficiency in patients with gastrointestinal tumors in Xinjiang(P<0.05).Conclusion Due to the affect of many fact

关 键 词：新疆地区 胃肠道肿瘤 维生素 流行病学 

分 类 号：R735[医药卫生—肿瘤]