内镜下套扎和组织胶注射治疗食管和胃底静脉曲张的效果分析  

Effect analysis of endoscopic ligation and tissue glue injection in the treatment of esophageal and gastric varices

作　　者：刘倩怡[1] 刘智尚[1] 李杰峰[1] 黎嘉妍 LIU Qian-yi;LIU Zhi-shang;LI Jie-feng(Digestive Department,Zhongshan People's Hospital,Zhongshan 528400,China)

机构地区：[1]广东省中山市人民医院消化内科,528400

出　　处：《中国实用医药》2023年第12期13-16,共4页China Practical Medicine

摘　　要：目的 探讨内镜下套扎和组织胶注射治疗食管和胃底静脉曲张患者的临床效果。方法 82例食管和胃底静脉曲张患者,随机分为对照组和观察组,各41例。对照组使用组织胶注射治疗,观察组使用内镜下套扎治疗。比较两组患者临床疗效、并发症发生率、再出血率、治疗次数、止血时间及治疗前后胃镜特征变化、门脉血流速度。结果 观察组治疗总有效率为97.56%,明显高于对照组的78.05%,差异具有统计学意义(P<0.05)。观察组并发症发生率7.32%及再出血率4.88%均低于对照组的31.71%、19.51%,差异具有统计学意义(P<0.05)。观察组止血时间(9.24±3.15)min明显短于对照组的(12.11±4.03)min,差异具有统计学意义(P<0.05)。治疗6个月,观察组曲张静脉数目(1.49±0.62)个、静脉曲张直径(0.78±0.20)cm及红色征比例21.95%均优于对照组的(3.27±0.45)个、(1.09±0.18)cm、58.54%,差异具有统计学意义(P<0.05)。两组治疗6个月门静脉、脾静脉血流速度大于治疗前,差异具有统计学意义(P<0.05);观察组治疗6个月脾静脉血流速度(32.95±2.62)cm/s大于对照组的(30.27±2.06)cm/s,差异具有统计学意义(P<0.05)。结论 内镜下套扎治疗食管和胃底静脉曲张患者的临床效果显著,防治再出血的效果更好,有效改变了内镜特征,安全性高,可优先选择。Objective To discuss the clinical effect of endoscopic ligation and tissue glue injection in the treatment of esophageal and gastric varices.Methods A total of 82 patients with esophageal and gastric varices were randomly divided into control group and observation group,with 41 cases in each group.The control group was treated with tissue glue injection,and the observation group was treated with endoscopic ligation.Both groups were compared in terms of clinical efficacy,complication rate,rebleeding rate,treatment times,hemostatic time,changes in gastroscopy characteristics before and after treatment,and portal blood flow velocity.Results The total effective rate of the observation group was 97.56%,which was significantly higher than that of 78.05%of the control group,and the difference was statistically significant(P<0.05).The complication rate of 7.32%and rebleeding rate of 4.88%in the observation group were lower than those of 31.71%and 19.51%in the control group,and the differences were statistically significant(P<0.05).The hemostatic time of(9.24±3.15)min in the observation group was significantly shorter than that of(12.11±4.03)min in the control group,and the difference was statistically significant(P<0.05).After 6 months of treatment,the number,diameter and red sign ratio of varicose veins were(1.49±0.62)veins,(0.78±0.20)cm and 21.95%in the observation group,which were better than those of(3.27±0.45)veins,(1.09±0.18)cm and 58.54%in the control group,and the differences were statistically significant(P<0.05).The portal and splenic venous blood flow velocity in the two groups after 6 months of treatment was higher than that before treatment in this group,and the difference was statistically significant(P<0.05).After 6 months of treatment,the splenic venous blood flow velocity of(32.95±2.62)cm/s in the observation group was higher than that of(30.27±2.06)cm/s in the control group,and the difference was statistically significant(P<0.05).Conclusion Endoscopic ligation is significantly effective in the t

关 键 词：食管和胃底静脉曲张 内镜下套扎 组织胶注射 临床效果 

分 类 号：R57[医药卫生—消化系统]