眼部湿化氧疗对高原地区硬核白内障超声乳化术后角膜水肿的疗效研究  

Therapeutic effect of eye humidification oxygen therapy on corneal edema after phacoemulsification for hard nucleus cataract in high altitude areas

作　　者：阮明辉 黄婷婷 李学蕊 查超英 袁创 RUAN Minghui;HUANG Tingting;LI Xuerui;ZHA Chaoying;YUAN Chuang(Department of Ophthalmology,the Second Affiliated Hospital of Kunming Medical University,Kunming,Yunnan 650106,China)

机构地区：[1]昆明医科大学第二附属医院院眼科,云南昆明650106

出　　处：《现代医药卫生》2023年第13期2222-2227,共6页Journal of Modern Medicine & Health

摘　　要：目的 探讨眼部湿化氧疗对高原地区硬核白内障超声乳化术后角膜水肿的疗效。方法 选取2022年6-10月该院行白内障超声乳化抽吸联合人工晶体植入术的硬核白内障患者69例(69眼),将其分为对照组[35例(35眼)]和观察组[34例(34眼)]。对照组行常规治疗,观察组在对照组基础上行眼部湿化氧疗。比较2组角膜内皮细胞计数(ECC)、平均细胞面积(AVG)、变异系数(CV)、六边形细胞百分比(HEX)、中央角膜厚度(CCT)、内皮细胞丢失率、角膜水肿好转情况、术中超声乳化时间及超声乳化能量。结果 2组术前角膜ECC、AVG、CV、HEX水平比较,差异无统计学意义(P>0.05)。2组术后角膜ECC、AVG、CV、HEX水平及内皮细胞丢失率比较,差异有统计学意义(P<0.05)。观察组术后1个月时角膜ECC、AVG、CV、HEX水平与术前比较,差异有统计学意义(P<0.001)。2组术中超声乳化时间及超声乳化能量比较,差异无统计学意义(P>0.05)。观察组术后2、3、5 d时角膜水肿好转情况优于对照组,差异有统计学意义(P<0.05)。观察组术后2、3、5、7、14 d时CCT水平显著低于对照组,差异有统计学意义(P<0.001)。结论 眼部湿化氧疗可加快硬核白内障超声乳化术后角膜水肿患者恢复速度,降低角膜内皮细胞丢失率。Objective To explore the therapeutic effect of eye humidification oxygen therapy on corneal edema after phacoemulsification for hard nucleus cataract in high altitude areas.Methods A total of 69 patients(69 eyes)with hard nucleus cataract who underwent cataract phacoemulsification combined with intraocular lens implantation in the hospital from June to October 2022 were divided into the control group[35 cases(35 eyes)]and the observation group[34 cases(34 eyes)].The control group received routine treatment,while the observation group received eye humidification oxygen therapy on the basis of the control group.The corneal endothelial cell count(ECC),average cell area(AVG),coefficient of variation(CV),hexagonal cell percentage(HEX),central corneal thickness(CCT),endothelial cell loss rate,improvement of corneal edema,intraoperative phacoemulsification time,and phacoemulsification energy were compared between the two groups.Results There were no statistically significant differences in the levels of corneal ECC,AVG,CV,and HEX before surgery between the two groups(P>0.05).There were statistically significant differences in the levels of corneal ECC,AVG,CV,HEX,and endothelial cell loss rate after surgery between the two groups(P<0.05).The levels of corneal ECC,AVG,CV and HEX in the observation group at one month after operation were significantly different from those before operation.(P<0.001).There were no statistically significant differences in the intraoperative phacoemulsification time and phacoemulsification energy between the two groups(P>0.05).The improvements of corneal edema at 2,3,5 days after surgery in the observation group were better than those in the control group,with statistically significant differences(P<0.05).The CCT levels at 2,3,5,7,14 days after surgery in the observation group were significantly lower than those in the control group,with statistically significant differences(P<0.001).Conclusion Eye humidification oxygen therapy can accelerate the recovery rate of patients with corneal edema af

关 键 词：眼部湿化氧疗 硬核白内障 角膜水肿 白内障超声乳化 

分 类 号：R776.1[医药卫生—眼科]