乳腺化生性癌临床特点及超声表现  

Clinical features and ultrasonic manifestations of metaplastic breast carcinoma

作　　者：李静敏 邵玉红[1] 孙秀明[1] 梁振威 LI Jingmin;SHAO Yuhong;SUN Xiuming;LIANG Zhenwei(Department of Ultrasound,Peking University First Hospital,Beijing 100034,China)

机构地区：[1]北京大学第一医院超声医学科,北京100034

出　　处：《中国介入影像与治疗学》2023年第7期419-422,共4页Chinese Journal of Interventional Imaging and Therapy

摘　　要：目的观察乳腺化生性癌(MBC)的临床特点及超声表现。方法回顾性分析经手术病理证实的37例单发MBC与74例乳腺非特殊型浸润性癌(IC-NST)患者(74个病灶)的临床资料及病灶超声表现。结果37个MBC病灶中,32个呈低回声、5个呈囊实性回声;9个呈规则椭圆形,28个形态不规则;14个边缘光整,13个内见点状强回声微钙化,2个后方回声衰减;35个肿瘤均呈平行生长;CDFI示29个为AdlerⅡ或Ⅲ级血流。MBC与IC-NST患者之间,Ki-67表达、雌激素受体(ER)阳性、孕激素受体(PR)阳性、就诊原因、自觉肿物生长迅速与否、有无腋窝淋巴结转移,以及肿瘤最大径、回声、形态、边缘、方位及后方回声衰减差异均有统计学意义(P均<0.05);患者年龄、人表皮生长因子受体2(HER-2)阳性及肿瘤微钙化及Adler血流分级差异均无统计学意义(P均>0.05)。结论MBC临床及超声表现均有一定特异性,有助于诊断。Objective To observe the clinical features and ultrasonic manifestations of metaplastic breast carcinoma(MBC).Methods Clinical and ultrasonic data of 37 patients with single MBC lesions and 74 patients with single breast invasive carcinoma of no special type(IC-NST)confirmed by postoperative pathology were retrospectively analyzed.Results Among 37 MBC lesions,32 were hypoechoic while 5 were cystic-solid lesions,9 were shaped ovally and 28 were shaped irregularly.Well-defined margins were found in 14 lesions,microcalcifications were observed in 13 lesions,while posterior acoustic attenuation was noticed in 2 lesions.Parallel growth was found in 35 lesions.CDFI showed AdlerⅡorⅢgrade blood flow in 29 lesions.There were significant differences in Ki-67 expression,estrogen receptor(ER)positivity,progesterone receptor(PR)positivity,reasons for consultation,rapid self-perceived growth of the tumor,axillary lymph node metastasis,the tumor maximum diameter,echo,shape,margin,orientation and posterior acoustic attenuation of lesions(all P<0.05),whereas there was no significant difference of age,human epidermal growth factor receptor 2(HER-2)positivity,microcalcifications nor Adler blood flow grade between MBC and IC-NST(all P>0.05).Conclusion The clinical features and ultrasonic manifestations of MBC were specific to some degree,hence being helpful for diagnosis.

关 键 词：超声检查 乳腺化生性癌 非特殊型浸润性乳腺癌 

分 类 号：R737.9[医药卫生—肿瘤] R445.1[医药卫生—临床医学]