3种软件在头颈部肿瘤患者脑干结构自动勾画中的应用比较  

Comparison Study of Three Softwares for Automatic Delineation of Brain Stem Structure of Patients with Head and Neck Neoplasms

作　　者：王敏[1] 霍新颖[2] 时飞跃[1,3] 陈丽丽[1] 秦伟[1] 赵环宇[1] 魏晓为[1] WANG Min;HUO Xinying;SHI Feiyue;CHEN Lili;QIN Wei;ZHAO Huanyu;WEI Xiaowei(Radiation Therapy Center,Nanjing First Hospital,Nanjing Medical University(Nanjing First Hospital),Nanjing Jiangsu 210006,China;Department of Public Health,Nanjing First Hospital,Nanjing Medical University(Nanjing First Hospital),Nanjing Jiangsu 210006,China;Research Center of Medical Physics,Nanjing Medical University,Nanjing Jiangsu 210029,China)

机构地区：[1]南京医科大学附属南京医院(南京市第一医院)肿瘤放疗中心,江苏南京210006 [2]南京医科大学附属南京医院(南京市第一医院)公共卫生处,江苏南京210006 [3]南京医科大学医学物理研究中心,江苏南京210029

出　　处：《中国医疗设备》2023年第7期7-11,22,共6页China Medical Devices

基　　金：国家自然科学基金面上项目(81773240);江苏省自然科学基金面上项目(BK20181118);南京医科大学科技发展基金—一般项目(NMUB20210210)。

摘　　要：目的 比较PVMED-iCurve、AccuContour和DeepViewer 3种国产软件自动勾画头颈部肿瘤患者脑干结构的准确性。方法 选取2021年1月至2022年10月收治的20例头颈部肿瘤患者为研究对象,分别使用PVMED-iCurve、AccuContour以及DeepViewer3种软件自动勾画头颈部肿瘤患者脑干结构。以手动勾画作为参考标准,通过对比上述3种自动勾画的体积差异(△V%)、Hausdorff距离(Hausdorff Distance,HD)和Dice相似性系数(Dice Similarity Coefficient,DSC),评估3种软件自动勾画脑干结构的效果。结果 PVMED-iCurve、AccuContour和DeepViewer 3种软件自动勾画头颈部肿瘤患者脑干结构的ΔV%分别为6.01%±17.77%、-2.49%±9.33%以及-9.68%±11.17%;HD分别为(7.74±3.05)、(2.83±1.18)、(4.00±2.16)mm;DSC分别为0.81±0.05、0.89±0.05以及0.85±0.06。3种软件两两比较,DSC差异均有统计学意义(P<0.05)。结论 3种软件自动勾画头颈部肿瘤患者脑干结构,均能达到较好的勾画效果。3种软件比较,AccuContour在自动勾画脑干的体积、位置和形状方面最好。Objective To evaluate and compare the accuracy of three domestic softwares including PVMED-iCurve,AccuContour and DeepViewer on automatic delineation of the brain stem structure for patients with head and neck neoplasms.Methods A total of 20 patients with head and neck neoplasms were enrolled from January 2021 to October 2022.The brain stem structure of patients with head and neck neoplasms was automatically delineated by using PVMED-iCurve,AccuContour and DeepViewer respectively.Taking manual delineation as the reference standard,compared the results of volume difference(ΔV%),Hausdorff distance(HD),and Dice similarity coefficients(DSC)of the above three kinds of automatic delineation,the effect of the three kinds of software on automatic delineation of brain stem structure was evaluated.Results PVMED-iCurve,AccuContour and DeepViewer were used to automatically delineate the brain stem structure of patients with head and neck neoplasms,andΔV%were 6.01%±17.77%,-2.49%±9.33%and-9.68%±11.17%respectively.HD were(7.74±3.05),(2.83±1.18)and(4.00±2.16)mm respectively.DSC were 0.81±0.05,0.89±0.05 and 0.85±0.06 respectively.Pairwise comparison between the three software showed statistically significant differences in DSC(P<0.05).Conclusion The three kinds of software can automatically delineate the brain stem structure of patients with head and neck neoplasms,and all can achieve good sketching effect.Compared with the three kinds of software,AccuContour is best in volume,position and shape of automatically delineating the brain stem.

关 键 词：自动勾画 脑干 头颈部肿瘤 深度学习 国产软件 

分 类 号：R739.91[医药卫生—肿瘤]