胰管括约肌切开联合胰管支架治疗胆道微结石性急性特发性胰腺炎的效果及对胃肠功能的影响  

Effect of Pancreatic Sphincterotomy Combined with Pancreatic Stent in the Treatment of Acute Idiopathic Pancreatitis Caused by Biliary Microlithiasis and Its Influence on Gastrointestinal Function

作　　者：胡浔科 余亚萍 HU Xunke;YU Yaping(The Second People's Hospital of Jingdezhen,Jiangxi Province,Jingdezhen 333000,China)

机构地区：[1]江西省景德镇市第二人民医院,江西景德镇333000

出　　处：《中国医学创新》2023年第18期28-31,共4页Medical Innovation of China

基　　金：江西省卫生健康委科技计划项目(202120049)。

摘　　要：目的:探究及分析胰管括约肌切开联合胰管支架治疗胆道微结石性急性特发性胰腺炎的效果及对胃肠功能的影响。方法:将2019年5月-2021年5月景德镇市第二人民医院收治的81例胆道微结石性急性特发性胰腺炎患者作为研究对象,根据随机数字表法分为对照组40例和观察组41例。对照组采用内镜下括约肌切开联合胆道清理术进行治疗,观察组则采用胰管括约肌切开联合胰管支架治疗。比较两组的住院时间,术后不同时间的急性胰腺炎复发率,并发症发生率,手术前后的白细胞计数(WBC)、淀粉酶(AMY)、胰腺血流情况及胃肠功能指标[血清胃动素(MTL)、胃泌素(GAS)]。结果:观察组的住院时间显著短于对照组,术后6、12个月的急性胰腺炎复发率及并发症发生率均显著低于对照组,差异均有统计学意义(P<0.05)。术前两组的WBC、AMY、胰腺血流情况及胃肠功能指标比较,差异均无统计学意义(P>0.05);术后1、3 d观察组的WBC、AMY均显著低于对照组,胰腺血流均显著优于对照组,胃肠功能指标均显著高于对照组,差异均有统计学意义(P<0.05)。结论:胰管括约肌切开联合胰管支架在胆道微结石性急性特发性胰腺炎中的疗效较好,且对胃肠功能的影响相对较小。Objective:To investigate and analyze the effect of pancreatic sphincterotomy combined with pancreatic stent in the treatment of patients with acute idiopathic pancreatitis caused by biliary microlithiasis and influence on gastrointestinal function.Method:A total of 81 patients with acute idiopathic pancreatitis caused by biliary microlithiasis in the Second People's Hospital of Jingdezhen from May 2019 to May 2021 were selected,they were divided into the control group(40 cases)and observation group(41 cases)according to the random number table method.The control group was treated with pancreatic sphincterotomy combined with biliary tract cleaning,the observation group was treated with pancreatic sphincterotomy combined with pancreatic stent.Then the hospitalization time,recurrence rates of acute pancreatitis at different time after operation,the complication rates,white blood cell(WBC),amylase(AMY),pancreatic blood flow and gastrointestinal function indexes[serum motilin(MTL)and gastrin(GAS)]before and after the treatment of two groups were compared.Result:The hospitalization time of observation group was significantly shorter than that control group,the recurrence rates of acute pancreatitis at 6 and 12 months after operation and complication rates were significantly lower than those of control group,the differences were statistically significant(P<0.05).The WBC,AMY,pancreatic blood flow and gastrointestinal function indexes of two groups before the operation were compared,the differences were not statistically significant(P>0.05);the WBC and AMY of the observation group at 1 and 3 d after the operation were significantly lower than those of the control group,the pancreatic blood flow was significantly better than that of control group,the gastrointestinal function indexes were significantly higher than those of the control group,the differences were statistically significant(P<0.05).Conclusion:The effect of pancreatic sphincterotomy combined with pancreatic stent in the patients with acute idiopathic pancreatit

关 键 词：胰管括约肌切开 胰管支架 胆道微结石性急性特发性胰腺炎 胃肠功能 

分 类 号：R576[医药卫生—消化系统]