广西某三甲医院11824例健康体检人群子宫颈不典型鳞状细胞检测状况及与生殖道感染的关系  

Cervical Atypical Squamous Cell Detection and Its Relationship with Genital Tract Infection in 11,824 Healthy People in a Grade A Tertiary Hospital in Guangxi

作　　者：罗惠方 陈丽平[1] 李小珍[1] 韦晓英[1] 罗颖华[1] 蓝盈盈 黄小知 LUO Huifang;CHEN Liping;LI Xiaozhen;WEI Xiaoying;LUO Yinghua;LAN Yingying;HUANG Xiaozhi(People's Hospital of Guangxi Zhuang Autonomous Region,Nanning 530021,China)

机构地区：[1]广西壮族自治区人民医院,广西南宁530021

出　　处：《中国医学创新》2023年第18期152-155,共4页Medical Innovation of China

基　　金：广西壮族自治区卫生健康委员会科研课题(Z20190662;Z20210879)。

摘　　要：目的:分析子宫颈不典型鳞状细胞(atypicalsquamouscell,ASC)在健康体检人群中的检出情况及其与生殖道感染的关系。方法:选择2019年7-12月在广西壮族自治区人民医院体检中心进行体检的健康女性11824例为研究对象。所有研究对象均进行常规妇科检查、阴道分泌物检查、子宫颈脱落细胞检查。分析不同年龄段人群的子宫颈ASC检出率,采用logistic回归分析不同生殖道感染类型(包括阴道假丝酵母菌病、滴虫性阴道炎、细菌性阴道病、子宫颈腺囊肿、子宫颈肥大及息肉、子宫颈糜烂样改变等)与子宫颈ASC的关系。结果:11824例研究对象中共检出170例ASC,检出率为1.44%。不同年龄段女性的子宫颈ASC检出率差异有统计学意义(χ^(2)=43.145,P<0.001),其中20~29岁年龄组检出率最高,达3.36%(30/894)。阴道假丝酵母菌病、滴虫性阴道炎、子宫颈糜烂样改变及子宫颈腺囊肿患者的子宫颈ASC检出率均高于无阴道假丝酵母菌病、无滴虫性阴道炎、无子宫颈糜烂样改变及无子宫颈腺囊肿患者(P<0.05),而有无细菌性阴道病、有无子宫颈肥大及有无子宫颈息肉的子宫颈ASC检出率差异均无统计学意义(P>0.05)。logistic回归分析显示,阴道假丝酵母菌病、滴虫性阴道炎、子宫颈糜烂样改变、子宫颈腺囊肿是子宫颈ASC发生的影响因素(P<0.05)。结论:子宫颈ASC检出率在各年龄段的分布具有差异性,阴道假丝酵母菌病、滴虫性阴道炎、子宫颈糜烂样改变、子宫颈腺囊肿与ASC发生有关,因此存在以上生殖道感染的人群应定期进行子宫颈细胞学检查,并及时治疗阴道炎及子宫颈病变。Objective:To investigate the detection rate of atypical squamous cells(ASC)of the cervix in healthy people and its relationship with genital tract infection.Method:A total of 11,824 healthy women who underwent physical examination in the Physical Examination Center of People Hospital of Guangxi Zhuang Autonomous Region from July to December 2019 were selected as subjects.All subjects underwent routine gynecological examination,vaginal secretion examination and cervical exfoliation cell examination.The detection rate of cervical ASC in different age groups was analyzed,and logistic regression was used to analyze the relationship between cervical ASC and different types of reproductive tract infections(including vaginal candidiasis,trichomoniasis vaginitis,bacterial vaginosis,cervical glandular cysts,cervical hypertrophy and polyps,cervical erosion-like changes).Result:A total of 170 ASC were detected in 11,824 subjects,with a detection rate of 1.44%.There were statistically significant differences in the detection rates of ASC among different ages(χ^(2)=43.145,P<0.001),among which the detection rate of 20-29 years old was the highest,reaching 3.36%(30/894).The detection rates of cervical ASC in patients with vaginal candidiasis,trichomoniasis vaginitis,cervical erosion-like changes and cervical glandular cysts were higher than those in patients without vaginal candidiasis,trichomoniasis vaginitis,cervical erosion-like changes and cervical glandular cysts(P<0.05).There were no statistical significance in the detection rate of cervical ASC in patients with bacterial vaginosis,cervical hypertrophy and cervical polyp compared with those without bacterial vaginosis,cervical hypertrophy and cervical polyp(P>0.05).logistic regression analysis showed that vaginal candidiasis,trichomoniasis vaginitis,cervical erosion-like changes and cervical glandular cysts were the influencing factors for the occurrence of cervical ASC(P<0.05).Conclusion:The detection rate of cervical ASC is different in different age groups and ASC is

关 键 词：健康体检 子宫颈不典型鳞状细胞 生殖道感染 

分 类 号：R737.33[医药卫生—肿瘤]